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60063 Sigma-Aldrich

Potassium antimonyl tartrate trihydrate

purum p.a., 99.0-103% (RT)

Synonym: Antimony potassium tartrate trihydrate, Tartar emetic

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Properties

Related Categories Essential Chemicals, Potassium Salts, Research Essentials, Salts
InChI Key   WBTCZEPSIIFINA-UHFFFAOYSA-J
grade   purum p.a.
assay   99.0-103% (RT)
loss   ≤2.7% loss on drying
mp   ≥300 °C(lit.)
anion traces   chloride (Cl-): ≤100 mg/kg
  sulfate (SO42-): ≤500 mg/kg
cation traces   Ca: ≤50 mg/kg
  Cd: ≤50 mg/kg
  Co: ≤50 mg/kg
  Cu: ≤50 mg/kg
  Fe: ≤50 mg/kg
  Na: ≤500 mg/kg
  Ni: ≤50 mg/kg
  Pb: ≤50 mg/kg
  Zn: ≤50 mg/kg

Description

Application

Potassium antimonyl tartrate trihydrate may be used as an Sb(III)-containing drug to investigate its ability to induce cell death associated with DNA fragmentation in axenic amastigotes of Leishmania infantum.

General description

Potassium antimonyl tartrate trihydrate is a trivalent antimony compound. It has been reported to be a leishmanicidal compound and exhibits more toxic action than pentavalent antimony (Pentostam) against Leishmania species. Three-dimensional X-ray and white radiation neutron diffraction methods have been reported to investigate the crystal structure of its optically active form (dipotassium di-μ-d-tartrato (4)-bis(antimonate(III)) trihydrate). Unit cell dimensions reported were: a = 11.192(2), b = 11.696(3), and c = 25.932(5)Å.

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Laboratory Gloves
Safety & Documentation

Safety Information

Symbol 
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
RIDADR 
UN 1551 6.1 / PGIII
WGK Germany 
3
RTECS 
CC6825000
Protocols & Articles
Peer-Reviewed Papers
15

References

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