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63174 Sigma-Aldrich

4-Maleimidobutyric acid

≥98.0% (T)

Synonym: γ-Maleimidobutyric acid, 4-Maleimidobutanoic acid, N-(3-Carboxypropyl)maleimide, N-Maleoyl-4-aminobutyric acid, N-Maleoyl-GABA

  • CAS Number 57078-98-5

  • Empirical Formula (Hill Notation) C8H9NO4

  • Molecular Weight 183.16

  •  Beilstein Registry Number 1455876

  •  MDL number MFCD00043139

  •  PubChem Substance ID 329759801

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Properties

InChI Key   NCPQROHLJFARLL-UHFFFAOYSA-N
assay   ≥98.0% (T)
mp   95-98 °C

Description

Other Notes

SH-label for the modification of peptides and proteins; Used for the preparation of a new bleomycin analog for enzyme immunoassay (EIA); probe for membrane SH-groups

Application

Gamma-maleimidobutyric acid may be used as a spacer in the construction of drug and other types of bioconjugates. 4-Maleimidobutyric acid is used with N-hydroxysuccinimide ester as a bifunctional cross-linking agent.

Modification reagent for thiol groups in proteins

Price and Availability


Laboratory Gloves
Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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