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70990 Sigma-Aldrich

α-Cyano-4-hydroxycinnamic acid

matrix substance for MALDI-MS, ≥99.0% (HPLC)

Synonym: α-CCA, α-CHCA, α-Cyano, 4-HCCA, ACCA

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Properties

Related Categories Analytical Reagents, Analytical/Chromatography, Mass Spectrometry (MS), Matrix Substances for MALDI-MS, Spectroscopy More...
grade   matrix substance for MALDI-MS
InChI Key   AFVLVVWMAFSXCK-VMPITWQZSA-N
assay   ≥99.0% (HPLC)
mp   245-250 °C(lit.)
  245-250 °C
solubility   methanol: 10 mg/mL clear
cation traces   Ba: ≤5 mg/kg
  Ca: ≤10 mg/kg
  Cd: ≤5 mg/kg
  Co: ≤5 mg/kg
  Cr: ≤5 mg/kg
  Cu: ≤5 mg/kg
  K: ≤5 mg/kg
  Mg: ≤5 mg/kg
  Mn: ≤5 mg/kg
  Na: ≤10 mg/kg
  Ni: ≤5 mg/kg
  Pb: ≤5 mg/kg
  Zn: ≤5 mg/kg
absorption   absorption/337 nm ≥2000 (mol. absorption)
analyte suitability   glycans
  peptides
  proteins

Description

Frequently Asked Questions

Frequently Asked Questions are available for this Product.

Other Notes

Matrix substance used in MALDI-MS (matrix-assisted laser desorption ionization MS) peptide analysis in proteomics.

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Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis. These documents are located on the product detail page under Useful Links & Tools. Click on the following link to search for a Certificate of Analysis. Please click the following link to see the details on our Product Dating Information.
How do I get lot-specific information or a Certificate of Analysis?
A Certificate of Analysis is available by lot number and can be obtained through our Advanced Search Option: http://www.sigmaaldrich.com/catalog/AdvancedSearchPage.do
How do I find price and availability?
There are several ways to find pricing and availability for our products.  Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers. 
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS. To access the shipping information for this material, use the link on the product detail page for the product, or search here. 
My question is not addressed here, how can I contact Technical Service for assistance?
Use the option to the right to "Ask a Question" by email of a Technical Service Scientist.
What is the appearance of Product 70990, α-Cyano-4-hydroxycinnamic acid?
Catalog number 70990 is a powder, and has an appearance specification of faintly yellow to yellow in color.
What is the shelf life of Product 70990, α-Cyano-4-hydroxycinnamic acid?
This product does not have an Expiration or Recommended Re-Test date established for it.  As with all Sigma-Aldrich products, it is guaranteed up to a year from date of shipment. Please view our policy for Product Dating and Shipping at our website: http://www.sigmaaldrich.com/etc/medialib/docs/Sigma-Aldrich/General_Information/product-dating-information-statementv4.Par.0001.File.tmp/product-dating-information-statement-v4.pdf
What can be used for solublization of α-Cyano-4-hydroxycinnamic acid?
α-Cyano-4-hydroxycinnamic acid (α-CCA, α-CHCA, α-Cyano, 4-HCCA, ACCA) is soluble in methanol (up to 50 mg/ml). It is also soluble at 10 mg/ml using 50% acetonitrile in 0.05% TFA for MALDI-MS. The acetonitrile concentration can be adjusted for individual preferences. For biological applications, it has been solubilized at 100 mM in DMSO or 50 mM in ethanol.
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Protocols & Articles
Peer-Reviewed Papers
15

References

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