72800 Sigma-Aldrich


for spectrophotometric det. of amino sugars, ≥99.0%

  • CAS Number 555-16-8

  • Linear Formula O2NC6H4CHO

  • Molecular Weight 151.12

  •  Beilstein Registry Number 386796

  •  EC Number 209-084-5

  •  MDL number MFCD00007346

  •  PubChem Substance ID 24886452



Related Categories Aldehydes, Analytical Reagents, Analytical/Chromatography, Building Blocks, C7,
assay   ≥99.0% (HPLC)
quality   for spectrophotometric det. of amino sugars
ign. residue   ≤0.05%
mp   103-106 °C(lit.)
  104-106 °C


Other Notes

Reagent for the spectrophotometric det. of amino carbohydrates1

Same product — same quality — now Sigma-Aldrich brand

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Safety Information

GHS07  GHS07
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WGK Germany 


Certificate of Analysis

Protocols & Articles

Peer-Reviewed Papers


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1. A. Nakamura et al. Chem. Pharm. Bull. 17, 770, (1969)

Investigation of DNA as a catalyst for Henry reaction in water. Fan J, Sun G, Wan C, et al. Chem. Commun. (Camb.) (32), 3792-4, (2008)


Small peptides catalyze highly enantioselective direct aldol reactions of aldehydes with hydroxyacetone: unprecedented regiocontrol in aqueous media. Tang Z, Yang ZH, Cun LF, et al. Org. Lett. 6(13), 2285-7, (2004)


Helical polymer as mimetic enzyme catalyzing asymmetric aldol reaction. Zhang D, Ren C, Yang W, et al. Macromol. Rapid Commun. 33(8), 652-7, (2012)


Povarov reactions involving 3-aminocoumarins: synthesis of 1,2,3,4-tetrahydropyrido[2,3-c]coumarins and pyrido[2,3-c]coumarins. Kudale AA, Kendall J, Miller DO, et al. J. Org. Chem. 73(21), 8437-47, (2008)


Quantitative chemical derivatization technique in time-of-flight secondary ion mass spectrometry for surface amine groups on plasma-polymerized ethylenediamine film. Kim J, Shon HK, Jung D, et al. Anal. Chem. 77(13), 4137-41, (2005)


Enantioselective nitroaldol (Henry) reaction using copper(II) complexes of (-)-sparteine. Maheswaran H, Prasanth KL, Krishna GG, et al. Chem. Commun. (Camb.) (39), 4066-8, (2006)


Size-dependent catalysis by DABCO-functionalized Zn-MOF with one-dimensional channels. Gu JM, Kim WS, and Huh S Dalton Trans. 40(41), 10826-9, (2011)


Hydrolase-catalyzed fast Henry reaction of nitroalkanes and aldehydes in organic media. Wang JL, Li X, Xie HY, et al. J. Biotechnol. 145(3), 240-3, (2010)


Experimental and computational characterization of the 17O quadrupole coupling and magnetic shielding tensors for p-nitrobenzaldehyde and formaldehyde. Wu G, Mason P, Mo X, et al. J. Phys. Chem. A 112(5), 1024-32, (2008)


Aldol reactions catalyzed by L-proline functionalized polymeric nanoreactors in water. Lu A, Cotanda P, Patterson JP, et al. Chem. Commun. (Camb.) 48(78), 9699-701, (2012)


A perfusion-based micro opto-fluidic system (PMOFS) for continuously in-situ immune sensing. Tseng YT, Yang CS, and Tseng FG Lab Chip 9(18), 2673-82, (2009)


Promiscuous protease-catalyzed aldol reactions: a facile biocatalytic protocol for carbon-carbon bond formation in aqueous media. Li C, Zhou YJ, Wang N, et al. J. Biotechnol. 150(4), 539-45, (2010)


Synthesis and characterization of bioactive zinc(II) and cadmium(II) complexes with new Schiff bases derived from 4-nitrobenzaldehyde and acetophenone with ethylenediamine. Prakash A, Singh BK, Bhojak N, et al. Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 76(3-4), 356-62, (2010)


A study on quantum chemical calculations of 3-, 4-nitrobenzaldehyde oximes. Gökce H and Bahçeli S Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 79(5), 1783-93, (2011)


Microwave-assisted and efficient solvent-free knoevenagel condensation. A sustainable protocol using porous calcium hydroxyapatite as catalyst. Mallouk S, Bougrin K, Laghzizil A, et al. Molecules 15(2), 813-23, (2010)


Proline-beta(3)-amino-ester dipeptides as efficient catalysts for enantioselective direct aldol reaction in aqueous medium. De Nisco M, Pedatella S, Ullah H, et al. J. Org. Chem. 74(24), 9562-5, (2009)


Biochemical properties of human dehydrogenase/reductase (SDR family) member 7. Stambergova H, Skarydova L, Dunford JE, et al. Chem. Biol. Interact. 207, 52-7, (2014)


A block copolymer covalent coating acting as surfactants in separation of 2-[hydroxy(4-nitrophenyl)methyl]-cyclopent-2-enone and 4-nitrobenzaldehyde by capillary electrophoresis. Qiao J, Qi L, Ma H, et al. Talanta 80(2), 770-6, (2009)


Influence of hydroxypropylcyclodextrins on the toxicity of mixtures. Lin Z, Kong D, Zhong P, et al. Chemosphere 58(9), 1301-6, (2005)


Synthesis, spectroscopic and cytotoxic studies of biologically active new schiff bases derived from p-nitrobenzaldehyde. Iqbal A, Siddiqui HL, Ashraf CM, et al. Chem. Pharm. Bull. 55(7), 1070-2, (2007)


The mimic of type II aldolases chemistry: asymmetric synthesis of beta-hydroxy ketones by direct aldol reaction. Lu Z, Mei H, Han J, et al. Chem. Biol. Drug Des. 76(2), 181-6, (2010)


Sequential patterning of two fluorescent streptavidins assisted by photoactivatable biotin on an aminodextran-coated surface. Ahn J, Shin YB, Chang WS, et al. Colloids Surf. B Biointerfaces 87(1), 67-72, (2011)


Substrate profiling and aldehyde dismutase activity of the Kvβ2 subunit of the mammalian Kv1 potassium channel. Alka K, Ryan BJ, Dolly JO, et al. Int. J. Biochem. Cell Biol. 42(12), 2012-8, (2010)


Use of MEKC for the analysis of reactant and product of Baylis-Hillman reaction. Qi L, Cui K, Qiao J, et al. J. Sep. Sci. 32(9), 1480-6, (2009)


Identification, cloning and characterization of an aldo-keto reductase from Trypanosoma cruzi with quinone oxido-reductase activity. Garavaglia PA, Cannata JJ, Ruiz AM, et al. Mol. Biochem. Parasitol. 173(2), 132-41, (2010)


Enhancing the synthetic utility of aldolase antibody 38C2. Mondal K, Ramesh NG, Roy I, et al. Bioorg. Med. Chem. Lett. 16(4), 807-10, (2006)


Beil. 7,IV,598

Aldrich MSDS 1, 1354:A / Corp MSDS 1 (2), 2552:B / FT-IR 2 (2), 2532:D / FT-IR 1 (2), 112:D / FT-NMR 1 (2), 945:A / IR-Spectra (3), 915:H / IR-Spectra (2), 801:F / NMR-Reference 2 (2), 111:B / RegBook 1 (2), 1719:F / Sax 6, 2009 / Sigma FT-IR 1 (2), 776:C / Structure Index 1, 273:A:2

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