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75035 Sigma-Aldrich

Mettler-Toledo Calibration substance ME 18872, Caffeine

analytical standard, for the calibration of the thermosystem 900, traceable to primary standards (LGC)

Synonym: 1,3,7-Trimethylxanthine, Caffeine

  • CAS Number 58-08-2

  • Empirical Formula (Hill Notation) C8H10N4O2

  • Molecular Weight 194.19

  •  Beilstein Registry Number 17705

  •  EC Number 200-362-1

  •  MDL number MFCD00005758

  •  PubChem Substance ID 329766076

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, Melting Point Standards, Physical Properties Standards
grade   analytical standard
  for the calibration of the thermosystem 900
InChI Key   RYYVLZVUVIJVGH-UHFFFAOYSA-N
form   neat
quality   traceable to primary standards (LGC)
shelf life   limited shelf life, expiry date on the certificate and label
mp   234-236.5 °C(lit.)
format   neat
Gene Information   human ... ADORA1(134), ADORA2B(136), ADORA3(140), PDE4B(5142)
mouse ... Adora2b(11541)
rat ... Adora1(29290), Adora2a(25369)

Description

Frequently Asked Questions

Frequently Asked Questions are available for this Product.

Other Notes

Same product — same quality — now Sigma-Aldrich brand

Biochem/physiol Actions

A central nervous system stimulant believed to act through adenosine receptors and monoamine neurotransmitters. It is an adenosine receptor antagonist and adenosine 3′,5′-cyclic monophosphate (cAMP) phosphodiesterase inhibitor. Thus, levels of cAMP increase in cells following treatment with caffeine. It has been reported to affect cellular calcium levels, releasing calcium from intracellular stores. It overrides the cell cycle effects of various chemicals such as protease inhibitors, preventing apoptosis; and it has been shown to inhibit cellular DNA repair mechanisms.

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.



Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
EV6475000

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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