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76887 Sigma-Aldrich

1,4-Dioxane

analytical standard

Synonym: Diethylene oxide, Dioxane

  • CAS Number 123-91-1

  • Empirical Formula (Hill Notation) C4H8O2

  • Molecular Weight 88.11

  •  Beilstein Registry Number 102551

  •  EC Number 204-661-8

  •  MDL number MFCD00006571

  •  PubChem Substance ID 329767413

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Properties

Related Categories Additional Standards, Alpha Sort, Analytical Standards, Analytical/Chromatography, Chemical Class,
grade   analytical standard
vapor density   3 (vs air)
vapor pressure   27 mmHg ( 20 °C)
  40 mmHg ( 25 °C)
InChI Key   RYHBNJHYFVUHQT-UHFFFAOYSA-N
assay   ≥99.9% (GC)
form   neat
autoignition temp.   356 °F
shelf life   limited shelf life, expiry date on the label
expl. lim.   22 %
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
refractive index   n20/D 1.422(lit.)
  n20/D 1.422
bp   100-102 °C(lit.)
mp   10-12 °C(lit.)
density   1.034 g/mL at 25 °C(lit.)
format   neat

Description

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Price and Availability

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
Supplemental Hazard Statements 
May form explosive peroxides., Repeated exposure may cause skin dryness or cracking.
RIDADR 
UN1165 - class 3 - PG 2 - Dioxane
WGK Germany 
2
RTECS 
JG8225000
Flash Point(F) 
53.6 °F
Flash Point(C) 
12 °C
Protocols & Articles

Articles

GC Analysis of Industrial Solvents on Equity®-1

From our library of Articles, Sigma-Aldrich presents GC Analysis of Industrial Solvents on Equity®-1
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Purification, Size-exclusion chromatography

GC Analysis of Residual Solvents on SPB®-624 after SPME using 100 μm PDMS Fiber

From our library of Articles, Sigma-Aldrich presents GC Analysis of Residual Solvents on SPB®-624 after SPME using 100 μm PDMS Fiber
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Pharmaceutical, Purification, Sample preparations, Solid phase microextractions

The Utility of Headspace Grade Solvents for the Analysis of Organic Volatile Impurities

Organic volatile impurities or “OVIs” sometimes remain behind in pharmaceutical preparations as a result of synthetic and manufacturing procedures. For reasons of health and safety, testing is done t...
Katherine Stenerson, Shyam Verma
Reporter US Volume 28.1
Keywords: Chromatography, Gas chromatography, Organic synthesis, Pharmaceutical, Solvents

US EPA Method 8270 (Appendix IX): GC Analysis of Semivolatiles on Equity®-5 (30 m x 0.25 mm I.D., 0.50 μm)

From our library of Articles, Sigma-Aldrich presents US EPA Method 8270 (Appendix IX): GC Analysis of Semivolatiles on Equity®-5 (30 m x 0.25 mm I.D., 0.50 μm)
Keywords: Chromatography, Gas chromatography, Mass selective detector, Purification

Peer-Reviewed Papers
15

References

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