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78781 Sigma-Aldrich

Phenyl isothiocyanate

for protein sequence analysis, ≥99.5% (GC)

Synonym: PITC

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Properties

Related Categories Amino Acid Analysis, Analytical Reagents, Analytical/Chromatography, Application Specific Reagents, Biochemicals and Reagents,
grade   for protein sequence analysis
InChI Key   QKFJKGMPGYROCL-UHFFFAOYSA-N
assay   ≥99.5% (GC)
refractive index   n20/D 1.649
  n20/D 1.6515(lit.)
bp   218 °C(lit.)
mp   −21 °C(lit.)
solubility   water: insoluble
density   1.132 g/mL at 20 °C(lit.)
storage temp.   2-8°C

Description

Application

Derivatizing reagent for primary and secondary amines. Used in sequencing peptides by Edman degradation and in amino acid analyses by HPLC.

Other Notes

On-sequencer pyridylethylation of cysteine residues after protection of amino groups by reaction with phenylisothiocyanate

Same product — same quality — now Sigma-Aldrich brand

Price and Availability

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN 2927 8(6.1) / PGII
WGK Germany 
3
RTECS 
NX9275000
Flash Point(F) 
190.4 °F
Flash Point(C) 
88 °C
Protocols & Articles
Peer-Reviewed Papers
15

References

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