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81242 Sigma-Aldrich

Poly(ethylene glycol)

tested according to Ph.Eur., 4,000

Synonym: Macrogol 4,000, PEG

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Properties

Related Categories Analytical/Chromatography, Essential Chemicals, Materials Science, PEG and Oligo Ethylene Glycol, Pharmacopoeia,
vapor density   >1 (vs air)
vapor pressure   <0.01 mmHg ( 20 °C)
form   solid
autoignition temp.   581 °F
pharmacopeia   testing conforms to Pharmacopeia
mol wt   mol wt 3500-4500

Description

Application

Poly(ethylene glycol) may be used in the following studies:
• For the modification of proteins to form the conjugates having increased circulating life and reduced immunogenicity and antigenicity.
• Preparation of hydrogels useful for the diffusion controlled delivery of proteins.
• Preparation of poly(ethylene glycol) dimethacrylate (PEGDM).

General description

Poly(ethylene glycol) (PEG) is a non-toxic water-soluble polymer. PEG term is used for the polymer chains with molecular weights below 20 000, while poly(ethylene oxide) (PEO) refers to the higher molecular weight polymers. PEG has various biomedical applications. It forms complexes with α-cyclodextrins. Engineering of PEG hydrogel particles by mesoporous silica (MS) templating method has been reported.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
TQ4050000

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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