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84360 Sigma-Aldrich

Salmine sulfate from salmon sperm

mixture of polypeptides, each with 4 arginine residues at the C-terminus

Synonym: Protamine sulfate

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Properties

mol wt   Mr 5000-10000
ign. residue   ≤5%
loss   ≤10% loss on drying

Description

Other Notes

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Salmine sulfate is widely used for the precipitation of nucleic acids [Separation of proteins from nucleic acids]; and can also be used for the precipitation of proteins [Protein fractionation on the basis of solubility in aqueous solutions of salts and organic solvents

Biochem/physiol Actions

Protamine facilitates direct transfection of microbial cells, and of human cells using cationic liposomes. Protamine effectively neutralizes the anticoagulation effects of heparin.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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