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92360 Sigma-Aldrich

Chlorotrimethylsilane

puriss., ≥99.0% (GC)

Synonym: TMCS, Trimethylchlorosilane, Trimethylsilyl chloride

  • CAS Number 75-77-4

  • Linear Formula (CH3)3SiCl

  • Molecular Weight 108.64

  •  Beilstein Registry Number 1209232

  •  EC Number 200-900-5

  •  MDL number MFCD00000502

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Properties

Related Categories Analytical Reagents, Analytical/Chromatography, Chemical Synthesis, Derivatization Reagents, Derivatization Reagents GC,
vapor density   3.7 (vs air)
vapor pressure   100 mmHg ( 25 °C)
InChI Key   IJOOHPMOJXWVHK-UHFFFAOYSA-N
grade   puriss.
assay   ≥99.0% (GC)
autoignition temp.   752 °F
expl. lim.   6.4 %
refractive index   n20/D 1.387(lit.)
bp   57 °C(lit.)
mp   −40 °C(lit.)
density   0.856 g/mL at 25 °C(lit.)

Description

Other Notes

Silylating agent

Same product — same quality — now Sigma-Aldrich brand

Price and Availability


Cross-Coupling Guide
Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Supplemental Hazard Statements 
Corrosive to the respiratory tract., Reacts violently with water.
RIDADR 
UN1298 - class 3 - PG 2 - Trimethylchlorosilane
WGK Germany 
1
RTECS 
VV2710000
Flash Point(F) 
-18.4 °F
Flash Point(C) 
-28 °C
Protocols & Articles

Articles

Silylating Reagents for GC-MS Compatible Derivatives of NSAIDs

Human and veterinary pharmaceuticals are a group of “emerging” contaminants,1, 2 some of which are produced in increasingly large volumes every year. The amounts produced are reaching quantities simi...
Luis-Alberto Martin
AnalytiX Volume 10 Article 2
Keywords: Anti-inflammatory agents, Derivatizations, Environmental, Gas chromatography, Gas chromatography mass spectrometry, Mass spectrometry, Metabolites, Pesticides, Pharmaceutical, Silylations, Veterinary

Peer-Reviewed Papers
15

References

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