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92822 Sigma-Aldrich

Picrylsulfonic acid solution

1 M in H2O

Synonym: 2,4,6-Trinitrobenzenesulfonic acid solution, TNBS

  • CAS Number 2508-19-2

  • Empirical Formula (Hill Notation) C6H3N3O9S

  • Molecular Weight 293.17

  •  Beilstein Registry Number 572358

  •  MDL number MFCD00064382

  •  PubChem Substance ID 329770176

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Properties

Related Categories Analytical Reagents, Analytical/Chromatography, Application Specific Reagents, Derivatization Reagents, Derivatization Reagents HPLC,
InChI Key   NHJVRSWLHSJWIN-UHFFFAOYSA-N
concentration   1 M in H2O
density   1.14 g/mL at 20 °C
absorption   ε/340 nm ≤6.5 × 102 M-1cm-1
shipped in   dry ice
storage temp.   −20°C

Description

Caution

decomposes when stored at temperatures ≥0°C with precipitate formation (picric acid)

Other Notes

Sales restrictions may apply

Same product — same quality — now Sigma-Aldrich brand

Application

Hydrophilic modifying reagent. Derivatives with amino compounds can be regenerated with hydrazine.

Picrylsulfonic acid (2,4,6-Trinitrobenzenesulfonic acid solution, TNBS) may be used in studies on the mechanisms of intracellular pH regulation. TNBS is used to induce inflammatory bowel disease (IBD)/colonic inflammation for studies on its mechanism and treatment.

Price and Availability

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
Supplemental Hazard Statements 
Explosive when dry.
RIDADR 
UN3379 - DOT UN3265_PG_1 class 3 - PG 1 - Desensitized explosive, liquid, n.o.s. (Diethyl Azodicarboxylate 40% solution in toluene)
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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