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E1271 Sigma-Aldrich

N-Ethylmaleimide

BioXtra, ≥98% (HPLC)

DOWNLOAD MSDS (PDF)

Synonym: NEM

N-Ethylmaleimide BioXtra, ≥98% (HPLC)
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Properties

Related Categories Apoptosis Inhibitors, Apoptosis and Cell Cycle, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,
product line   BioXtra
assay   ≥98% (HPLC)
impurities   ≤0.001% Phosphorus (P)
  ≤0.1% Insoluble matter
ign. residue   ≤0.1%
bp   210 °C(lit.)
mp   43-46 °C(lit.)
solubility   95% ethanol: soluble50 mg/mL, clear to slightly hazy (colorless to faint yellow)
anion traces   chloride (Cl-): ≤0.05%
  sulfate (SO42-): ≤0.05%
cation traces   Al: ≤0.0005%
  Ca: ≤0.0005%
  Cu: ≤0.0005%
  Fe: ≤0.0005%
  K: ≤0.005%
  Mg: ≤0.0005%
  Na: ≤0.005%
  Pb: ≤0.001%
  Zn: ≤0.0005%
storage temp.   2-8°C
Gene Information   human ... SLC6A3(6531), SLC6A4(6532)
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Description

Application

Reagent for the covalent modification of cysteine residues in proteins.

Biochem/physiol Actions

Augments currents from native M-channels in sympathetic neurons and acts as an opener for KCNQ2, KCNQ4 and KCNQ5 channels.

Sulfhydryl alkylating agent that inactivates NADP-dependent isocitrate dehydrogenase and many endonucleases.

Price and Availability

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