D-Mannitol

Papers

Extravascular transport of drugs in tumor tissue: effect of lipophilicity on diffusion of tirapazamine analogues in multicellular layer cultures. Frederik B Pruijn et al J. Med. Chem. 48, 1079-87, (2005)

---

Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Giulia Caron et al J. Med. Chem. 48, 3269-79, (2005)

---

Exploring the role of different drug transport routes in permeability screening. Pär Matsson et al J. Med. Chem. 48, 604-13, (2005)

---

Radical scavenging activity of protein from tentacles of jellyfish Rhopilema esculentum. Huahua Yu et al Bioorg. Med. Chem. Lett. 15, 2659-64, (2005)

---

Chemical constituents of the fruits of Morinda citrifolia (Noni) and their antioxidant activity. Bao-Ning Su et al J. Nat. Prod. 68, 592-5, (2005)

---

Design, synthesis, and evaluation of proline and pyrrolidine based melanocortin receptor agonists. A conformationally restricted dipeptide mimic approach. Xinrong Tian et al J. Med. Chem. 49, 4745-61, (2006)

---

Multiple N-methylation by a designed approach enhances receptor selectivity. Jayanta Chatterjee et al J. Med. Chem. 50, 5878-81, (2007)

---

Effect of structural and conformation modifications, including backbone cyclization, of hydrophilic hexapeptides on their intestinal permeability and enzymatic stability. Shmuel Hess et al J. Med. Chem. 50, 6201-11, (2007)

---

Novel cationic lipophilic peptides for oligodeoxynucleotide delivery. Enoch Chan et al Bioorg. Med. Chem. 15, 4091-7, (2007)

---

Caco-2 cell permeability and stability of two d-glucopyranuronamide conjugates of thyrotropin-releasing hormone. Susanne T Wessling et al Bioorg. Med. Chem. 15, 4946-50, (2007)

---

Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds. Bram Baert et al Bioorg. Med. Chem. 15, 6943-55, (2007)

---

Backbone cyclic peptidomimetic melanocortin-4 receptor agonist as a novel orally administrated drug lead for treating obesity. Shmuel Hess et al J. Med. Chem. 51, 1026-34, (2008)

---

Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Gustav Ahlin et al J. Med. Chem. 51, 5932-42, (2008)

---

Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Lourdes Santana et al J. Med. Chem. 51, 6740-51, (2008)

---

Inhibitory property of the Piper betel phenolics against photosensitization-induced biological damages. Soumyaditya Mula et al Bioorg. Med. Chem. 16, 2932-8, (2008)

---

Synthesis, characterization, antioxidant activity and DNA-binding studies of two rare earth(III) complexes with naringenin-2-hydroxy benzoyl hydrazone ligand. Tian-Rong Li et al Eur. J. Med. Chem. 43, 1688-95, (2008)

---

Novel keto-enamine Schiffs bases from 7-hydroxy-4-methyl-2-oxo-2H-benzo[h] chromene-8,10-dicarbaldehyde as potential antidyslipidemic and antioxidant agents. Koneni V Sashidhara et al Eur. J. Med. Chem. 43, 2592-6, (2008)

---

Syntheses and evaluation of glucosyl aryl thiosemicarbazide and glucosyl thiosemicarbazone derivatives as antioxidant and anti-dyslipidemic agents. Samir Ghosh et al Bioorg. Med. Chem. Lett. 19, 386-9, (2009)

---

Phenylaminopyrimidines as inhibitors of Janus kinases (JAKs). Christopher J Burns et al Bioorg. Med. Chem. Lett. 19, 5887-92, (2009)

---

Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Lei Du-Cuny et al Bioorg. Med. Chem. 17, 6983-92, (2009)

---

Antidyslipidemic and antioxidative activities of 8-hydroxyquinoline derived novel keto-enamine Schiffs bases. Koneni V Sashidhara et al Eur. J. Med. Chem. 44, 1813-8, (2009)

---

Synthesis of novel benzocoumarin derivatives as lipid lowering agents. Koneni V Sashidhara et al Bioorg. Med. Chem. Lett. 20, 3065-9, (2010)

---

Novel coumarin derivatives as potential antidyslipidemic agents. Koneni V Sashidhara et al Bioorg. Med. Chem. Lett. 20, 4248-51, (2010)

---

Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Francisco J Prado-Prado et al Bioorg. Med. Chem. 18, 2225-31, (2010)

---

Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Denis Fourches et al Chem. Res. Toxicol. 23, 171-83, (2010)

---

Synthesis and biological evaluation of N-aryl-1,4-dihydropyridines as novel antidyslipidemic and antioxidant agents. Atul Kumar et al Eur. J. Med. Chem. 45, 501-9, (2010)

---

Neural computational prediction of oral drug absorption based on CODES 2D descriptors. A Guerra et al Eur. J. Med. Chem. 45, 930-40, (2010)

---

Synthesis and anti-inflammatory activity of novel biscoumarin-chalcone hybrids. Koneni V Sashidhara et al Bioorg. Med. Chem. Lett. 21, 4480-4, (2011)

---

Synthesis of novel N-(2-hydroxy-2-p-tolylethyl)-amide and N-(2-oxo-2-p-tolylethyl)-amide derivatives and their antidyslipidemic and antioxidant activity. T Narender et al Bioorg. Med. Chem. Lett. 21, 6393-7, (2011)

---

QSAR-based permeability model for drug-like compounds. Rafael Gozalbes et al Bioorg. Med. Chem. 19, 2615-24, (2011)

---

Prediction of drug intestinal absorption by new linear and non-linear QSPR. Alan Talevi et al Eur. J. Med. Chem. 46, 218-28, (2011)

---

FDA-approved drug labeling for the study of drug-induced liver injury. Minjun Chen et al Drug Discov. Today 16, 697-703, (2011)

---

Translating Clinical Findings into Knowledge in Drug Safety Evaluation - Drug Induced Liver Injury Prediction System (DILIps). Zhichao Liu et al PLoS Comput. Biol. 7, e1002310, (2011)

---

Tailoring of integrin ligands: probing the charge capability of the metal ion-dependent adhesion site. Markus Bollinger et al J. Med. Chem. 55, 871-82, (2012)

---

Signaling role of fructose mediated by FINS1/FBP in Arabidopsis thaliana. Cho YH PLoS Genet. 7(1), e1001263, (2011)

---

Merck 14,5745

Beil. 1,IV,2841

FT-IR 1 (1), 186:C / FT-IR 2 (1), 270:A / FT-NMR 1 (1), 289:C / IR-Spectra (2), 105:C / IR-Spectra (3), 113:E / NMR-Reference 2 (2), 902:B / RegBook 1 (1), 187:J / Sax 6, 1525 / Sigma FT-IR 1 (1), 1097:C / Structure Index 1, 25:C:4