N6160 Sigma-Aldrich

Novobiocin sodium

meets USP testing specifications

DOWNLOAD MSDS (PDF)

Synonym: Novobiocin sodium salt

  • CAS Number 1476-53-5

  • Empirical Formula (Hill Notation) C31H35N2NaO11

  • Molecular Weight 634.61

  •  Beilstein Registry Number 3892910

  •  EC Number 216-023-6

  •  PubChem Substance ID 24897774

Description

Application

For the production of positively supercoiled plasmid DNA.1 Inhibitor of bacterial DNA gyrase and eukaryotic DNA topoisomerase.2 Inhibitor of retrovirus RNA-dependent DNA-polymerase.3

Biochem/physiol Actions

Mode of Action: Inhibits DNA synthesis by inhibiting the enzyme Topoisomerase II.
Antimicrobial spectrum: Gram-positive bacterial.

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