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A1028 Sigma-Aldrich

8-Anilino-1-naphthalenesulfonic acid

Synonym: N-Phenyl peri acid, ANS, ANSA

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Properties

Related Categories A, Alphabetical, Biochemicals and Reagents, Cell Biology, Fluorescent Indicators and Probes,
InChI Key   FWEOQOXTVHGIFQ-UHFFFAOYSA-N
assay   ≥97% (HPLC)
form   powder
mp   215-217 °C (dec.)(lit.)
solubility   DMF: soluble50 mg/mL

Description

Packaging

5, 25, 100 g in glass bottle

Application

8-Anilino-1-naphthalenesulfonic acid (ANS) has been used to study the thermal aggregation of BSA (bovine serum albumin).

Biochem/physiol Actions

8-Anilino-1-naphthalenesulfonic acid (ANS) is an important dye which is used to study the intermediate states in the folding/unfolding pathways of proteins. It is also useful to check the conformational changes involved with the aggregation of proteins. ANS is nonfluorescent in the aqueous solution, however, it fluoresces strongly upon binding to BSA (bovine serum albumin) and denatured proteins. It is used for the detection of albumin in the serum. ANS mainly interacts with the solvent exposed nonpolar (hydrophobic) sites.

Price and Availability


Tissue Diagnostics

All labs need water

Biomedical Applications
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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