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A10701 Sigma-Aldrich

Acetophenone

ReagentPlus®, 99%

Synonym: Methyl phenyl ketone

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Properties

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grade   ReagentPlus®
vapor density   4.1 (vs air)
vapor pressure   0.45 mmHg ( 25 °C)
  1 mmHg ( 15 °C)
InChI Key   KWOLFJPFCHCOCG-UHFFFAOYSA-N
assay   99%
form   liquid
autoignition temp.   1058 °F
refractive index   n20/D 1.534(lit.)
bp   202 °C(lit.)
mp   19-20 °C(lit.)
density   1.03 g/mL at 25 °C(lit.)

Description

Packaging

1 L in glass bottle

5, 100 mL in glass bottle

Application

Acetophenone was used to induce peak currents in M71 neurons using voltage clamp. It may be used in the synthesis of N-(1-phenylethyl)formamide, via Leuckart reaction.

General description

Acetophenone (AP, methyl phenyl ketone) is a common industrial solvent. It can be synthesized from 1-phenylethanol in the presence of PdAu-NPs-TiO2 (titanium dioxide-supported palladium gold bimetallic nanoparticles) hybrid. Its vacuum ultraviolet absorption spectrum shows absorption bands at 196, 191, 179 and 167mμ. AP reacts with α-naphtylphenylsilane in the presence of N-chelate ligands based on chiral oxazolines to undergo hydrosilylation with high enantioselectivity. It can also undergo hydrogenation reaction in the presence of different transition metal catalysts under different conditions.

Legal Information

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Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
UN 3334
WGK Germany 
1
RTECS 
AM5250000
Flash Point(F) 
168.8 °F
Flash Point(C) 
76 °C
Protocols & Articles
Peer-Reviewed Papers
15

References

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