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A1593 Sigma-Aldrich

Ampicillin

meets USP testing specifications

Synonym: D-(−)-α-Aminobenzylpenicillin, Ampicillin trihydrate

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Properties

Related Categories A - K, Analytical/Chromatography, Antibacterial, Antibiotics, Antibiotics A to Z,
grade   meets USP testing specifications
InChI Key   RXDALBZNGVATNY-CWLIKTDRSA-N
form   solid
color   white
mp   198-200 °C (dec.)(lit.)
solubility   H2O: soluble 10 g/L
suitability   meets USP testing specifications
Mode of action   cell wall synthesis | interferes
antibiotic activity spectrum   Gram-negative bacteria
  Gram-positive bacteria
storage temp.   2-8°C

Description

Application

Used to select for ampicillin resistance in mutated and transformed cells.

Biochem/physiol Actions

A β-lactam antibiotic with an amino group side chain attached to the penicillin structure. Penicillin derivative that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli . Mode of resistance: Cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.

Packaging

25g

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Price and Availability


Laboratory Gloves
Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
XH8425000

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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