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A5099 Sigma-Aldrich

N-Acetyl-L-cysteine

PharmaGrade, Ajinomoto, Manufactured under appropriate GMP controls for pharma or biopharmaceutical production, suitable for cell culture

Synonym: LNAC, NAC

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Properties

Related Categories A - H, Amino Acids, Amino acids, Analytical/Chromatography, Biochemicals and Reagents,
Quality Level   GMP-COMPENDIA
  GMP
biological source   from non-animal source
grade   Non-Compendial
InChI Key   PWKSKIMOESPYIA-BYPYZUCNSA-N
product line   PharmaGrade
assay   ≥98.5%
form   crystalline powder
mfr. no.   Ajinomoto
impurities   endotoxin, heavy metals, trace metals, tested
mp   106-108 °C(lit.)
solubility   H2O: ≥10 mg/mL
suitability   suitable for cell culture
foreign activity   cytotoxicity, tested

Description

Biochem/physiol Actions

Antioxidant and mucolytic agent. Increases cellular pools of free radical scavengers. Reported to prevent apoptosis in neuronal cells but induce apoptosis in smooth muscle cells. Inhibits HIV replication. May serve as a substrate for microsomal glutathione transferase.

Linkage

To request the Enhanced Quality Product Documentation for this product, submit a PharmaGrade Product Information Request Form. Please note that access to the Enhanced Quality Product Documentation for this product requires a confidentiality disclosure agreement.

Application

This product has been discontinued. no need to update

General description

PharmaGrade products are manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production. For more information on the PharmaGrade Program, visit sigma-aldrich.com/safc-pharmagrade.

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.



Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
HA1660000

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.1 During the oxi...
Biofiles Volume 2 Article 2
Keywords: Adhesion, Anti-inflammatory agents, Applications, Cancer, Cardiovascular, Catalysis, Diabetes, Diseases, Gene expression, Metabolism, Neurodegenerative Diseases, Peroxidations, Phosphorylations, Prebiotics, Probiotics, Reductions, Transcription, Transduction, Vitamins

Peer-Reviewed Papers
15

References

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