Synonym: AEBSF
CAS Number 30827-99-7
Empirical Formula (Hill Notation) C8H10FNO2S · HCl
Molecular Weight 239.69
Beilstein Registry Number 7604627
MDL number MFCD00132962
PubChem Substance ID 24278240
Popular Documents: Product Information Sheet (PDF) | Specification Sheet (PDF)
| Related Categories | A to C, A-AM, Bioactive Small Molecules, Biochemicals and Reagents, Broad Spectrum Inhibitors of Proteolytic Enzyme Classes, |
| Quality Level | PREMIUM |
| assay | ≥97% |
| solubility | H2O: soluble50 mg/mL (stable for up to six months if stored refrigerated at a pH of less than 7. If a pH of greater than 7 is required, pH adjustment should be made just prior to use.) |
| storage temp. | −20°C |
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Recommended concentrations for use are 0.1-1 mM.
Irreversible serine protease inhibitor. Inhibition constants are similar to those of PMSF and DFP. AEBSF has been shown to inhibit trypsin, chymotrypsin, plasmin kallikrein and thrombin. As an alternative to PMSF and DFP, AEBSF offers lower toxicity, improved solubility in water and improved stability in aqueous solutions. AEBSF has been used in cell culture in concentrations of up to 0.25 mM.
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