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B5887 Sigma-Aldrich

Sodium butyrate

≥98.5% (GC)

Synonym: Butyric acid sodium salt

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Description

Biochem/physiol Actions

Decreases Ca2+ release from intracellular stores. Inhibits histone deacetylase (HDAC). Induces apoptosis in several cell lines.

Caution

Hygroscopic

Packaging

1, 5 g in glass bottle

250 mg in glass bottle

Price and Availability

Suggested Laboratory Gloves


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Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
ET6400000
Protocols & Articles

Articles

Histone Modification and Chromatin Remodeling

Gene expression is governed by complex mechanisms including transcription factor binding to DNA and coordinated changes in chromatin structure. The primary protein components of chromatin are the his...
Savita Bagga, PhD.
BioFiles v7 n3, 2012, 10–16
Keywords: Acetylations, Amplification, Cancer, Cell culture, Chromatin immunoprecipitation, Cloning, DNA purification, Diseases, Gene expression, Immunoprecipitation, Indicators, Methylations, Microarray Analysis, PAGE, Polymerase chain reaction, Polymerase chain reaction - quantitative, Polymorphisms, Purification, Sequencing, Transcription, Whole genome amplification

Peer-Reviewed Papers
15

References

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EPI003 In Situ Histone Deacetylase (HDAC) Activity Fluorometric Assay Kit, 100 assays in 96 well plates
EPI004 Histone Deacetylase 3 (HDAC3) Activity Assay Kit, 100 assays in 96 well plates
EPI005 Histone Deacetylase 3 (HDAC3) Inhibitor Screening Kit, 100 assays in 96 well plates
EPI006 Histone Deacetylase 8 (HDAC8) Activity Assay Kit, 100 assays in 96 well plates
EPI007 Histone Deacetylase 8 (HDAC8) Inhibitor Screening Kit, 100 assays in 96 well plates
EPI008 Histone Deacetylase (HDAC) Inhibitor Set I, Set includes 6 inhibitors
EPI009 Histone Deacetylase (HDAC) Inhibitor Set II, Set includes 7 inhibitors

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