Synonym: Butyric acid sodium salt
|Related Categories||Bioactive Small Molecules, Bioactive Small Molecules for Epigenetic Research, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience,|
|Gene Information||mouse ... ENSMUSG00000061062(15181)|
Decreases Ca2+ release from intracellular stores. Inhibits histone deacetylase (HDAC). Induces apoptosis in several cell lines.
1, 5 g in glass bottle
250 mg in glass bottle
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|Precautionary statements||P261-P281-P305 + P351 + P338|
|Personal Protective Equipment||dust mask type N95 (US), Eyeshields, Gloves|
|Hazard Codes (Europe)||Xn|
|Risk Statements (Europe)||36/37/38-68|
|Safety Statements (Europe)||26-36/37|
Gene expression is governed by complex mechanisms including transcription factor binding to DNA and coordinated changes in chromatin structure. The primary protein components of chromatin are the his...
Savita Bagga, PhD.
BioFiles v7 n3, 2012, 10–16
Keywords: Acetylations, Amplification, Cancer, Cell culture, Chromatin immunoprecipitation, Cloning, DNA purification, Diseases, Gene expression, Immunoprecipitation, Indicators, Methylations, Microarray Analysis, PAGE, Polymerase chain reaction, Polymerase chain reaction - quantitative, Polymorphisms, Purification, Sequencing, Transcription, Whole genome amplification
Histone deacetylase inhibitors suppress TF-kappaB-dependent agonist-driven tissue factor expression in endothelial cells and monocytes. Wang J, Mahmud SA, Bitterman PB, Huo Y, Slungaard A J. Biol. Chem., 28408-18, (2007)
Design, synthesis, and evaluation of novel mutual prodrugs (hybrid drugs) of all-trans-retinoic acid and histone deacetylase inhibitors with enhanced anticancer activities in breast and prostate cancer cells in vitro. Lalji K Gediya et al J. Med. Chem. 51, 3895-904, (2008)
Carbonic anhydrase inhibitors. Inhibition of the beta-class enzymes from the fungal pathogens Candida albicans and Cryptococcus neoformans with aliphatic and aromatic carboxylates. Alessio Innocenti et al Bioorg. Med. Chem. 17, 2654-7, (2009)
Carbonic anhydrase inhibitors. Inhibition of the ?-class enzymes from the fungal pathogens Candida albicans and Cryptococcus neoformans with branched aliphatic/aromatic carboxylates and their derivatives. Fabrizio Carta et al Bioorg. Med. Chem. Lett. 21, 2521-6, (2011)
Inhibition of sodium butyrate-induced apoptosis in recombinant Chinese hamster ovary cells by constitutively expressing antisense RNA of caspase-3. Kim, N.S., and Lee, G.M. Biotechnol. Bioeng. 78, 217-228, (2002)
Corp MSDS 1 (1), 654:D / FT-IR 2 (1), 861:B / FT-NMR 1 (1), 850:B / RegBook 1 (1), 613:I / Sigma FT-IR 1 (1), 1372:A / Structure Index 1, 88:D:5
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