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D1054 Sigma-Aldrich

Dihydrorhodamine 123

≥95%

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Properties

Related Categories Alphabetical, Biochemicals and Reagents, Cell Biology, D, Fluorescent Enzyme Substrates,
InChI Key   FNEZBBILNYNQGC-UHFFFAOYSA-N
assay   ≥95%
form   powder
solubility   DMSO: >5 mg/mL
storage temp.   −20°C

Description

Application

Dihydrorhodamine 123 has been used for the detection of free intracellular radicals or ROS (reactive oxygen species).

Packaging

2, 10 mg in ampule

Substrates

Peroxidase substrate

Biochem/physiol Actions

Dihydrorhodamine 123 is used for the detection of ROS (reactive oxygen species). Presence of ROS oxidizes dihydrorhodamine 123 to the fluorescent derivative rhodamine 123. The reaction happens in the presence of a peroxidase or a similar catalyst.

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Mitochondrial Stress and ROS

Oxidative stress is implicated in the pathogenesis of lipotoxicity in both animal and human studies. Chronic oxidative stress is linked to insulin resistance in multiple tissues. Oxidative stress is ...
BioFiles 2011, 6.4, 22.
Keywords: Anti-inflammatory agents, Apoptosis, Cancer, Cell signaling, Cellular processes, Gene expression, Indicators, Metabolism, Oxidations, Respiratory

Peer-Reviewed Papers
15

References

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