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D54702 Sigma-Aldrich

Dichloroacetic acid

ReagentPlus®, ≥99%

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Properties

Related Categories Acids, Acids & Bases, Aerobic Glycolysis (the Warburg Effect), Cancer Metabolism, Cancer Research,
grade   ReagentPlus®
vapor density   4.5 (vs air)
vapor pressure   0.19 mmHg ( 20 °C)
assay   ≥99%
form   liquid
refractive index   n20/D 1.466(lit.)
bp   194 °C(lit.)
mp   9-11 °C(lit.)
density   1.563 g/mL at 25 °C(lit.)
storage temp.   2-8°C
Gene Information   human ... ALDH1A1(216), PDK1(5163)
rat ... Pdk1(116551)

Description

Packaging

100, 4×100, 500 mL in glass bottle

2.5 L in glass bottle

5, 100 g in glass bottle

General description

Dichloroacetic acid (DCA) is a chlorinated acetic acid that has been reported to be a mouse liver carcinogen. The varying degrees of swelling of polyester in different concentrations of DCA solution has been analyzed by phase-contrast microscopy. The efficiency of titanium dioxide (TiO2) nanoparticles to catalyze the photodegradation of DCA has been investigated.

Legal Information

ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

Price and Availability


All labs need water
Safety & Documentation

Safety Information

Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 1764 8 / PGII
WGK Germany 
2
RTECS 
AG6125000
Flash Point(F) 
235.4 °F
Flash Point(C) 
113 °C

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Aerobic Glycolysis and the Warburg Effect

The Warburg effect is the enhanced conversion of glucose to lactate observed in tumor cells, even in the presence of normal levels of oxygen. Otto Heinrich Warburg demonstrated in 1924 that cancer ce...
Keywords: Aerobic, Biofiles, Cancer, Cell proliferation, Clinical, Glycolysis, PAGE, Phosphorylations, Support, Transcription

Determination of Water Content in Dichloroacetic acid Using Karl Fischer Titration

The determination of water in carboxylic acids is usually straightforward provided the substances are soluble. Strong acids must be neutralized. Acetic acid and related compounds have a tendency to u...
Keywords: Esterifications, Titrations

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Molarity Calculator and Normality Calculator for Acids and Bases

The molarity calculator tool provides lab-ready directions describing how to prepare an acid or base solution of specified Molarity (M) or Normality (N) from a concentrated acid or base solution.  To...

Peer-Reviewed Papers
15

References

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