D5879 Sigma-Aldrich

Dimethyl sulfoxide

ReagentPlus®, ≥99.5%

Synonym: DMSO



Related Categories Dimethyl Sulfoxide (DMSO), Plastic Bottles, Solvent by Type, Solvent Bottles, Solvent Packaging Options,
grade   ReagentPlus®
vapor density   2.7 (vs air)
vapor pressure   0.42 mmHg ( 20 °C)
assay   ≥99.5%
autoignition temp.   573 °F
shelf life   Recommended retest period - 2 years
expl. lim.   42 %, 63 °F
impurities   ≤0.1% water (Karl Fischer)
refractive index   n20/D 1.479(lit.)
bp   189 °C(lit.)
mp   16-19 °C(lit.)
solubility   H2O: soluble(lit.)
  acetone: soluble(lit.)
  benzene: soluble(lit.)
  chloroform: soluble(lit.)
  ethanol: soluble(lit.)
density   1.10 g/mL(lit.)


Frequently Asked Questions

Frequently Asked Questions are available for this Product.

Biochem/physiol Actions

DMSO is a highly polar substance that can be used as an industrial solvent for organic and inorganic chemicals. It is also used as a protectant during cold storage of living cells. It is also useful for the oxidation of thiols and disulfides to sulfonic acids.


Supercools easily and remelts slowly at room temperature. Solidified product can be re-liquified by warming to room temperature without detriment to the product.

Other Notes

A -D suffix exists for administrative purposes only.
All -D packages are 100% the same product, same quality, same specification as the package sizes previously sold without a -D.


1, 6×1, 4 L in glass bottle

100, 500 mL in glass bottle

Note: D5879-1L in glass bottle /D5879-1L-D in poly bottle.

Legal Information

ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

Price and Availability

Safety & Documentation

Safety Information

WGK Germany 
Flash Point(F) 
188.6 °F
Flash Point(C) 
87 °C
Protocols & Articles


Determination of Water Content in Dimethyl sulfoxide Using Karl Fischer Titration

It is not possible to reproduce water determination in DMSO because DMSO alters the stoichiometry of the KF reaction. This shortcoming becomes even greater as the number of samples increases. For mor...
Keywords: Pharmaceutical, Solvents


Enzymatic Assay of Cathepsin B

This procedure applies to all products that have a specification for Cathepsin B activity, such as Sigma-Aldrich Product Numbers C0150 and C8571, determined by the liberation of 7-amino-4-methylcouma...
Keywords: Enzyme activity, Enzymology

Peer-Reviewed Papers


Set your institution to view full text papers.
Related Products

also commonly purchased with this product

Product #


Add to Cart

A2549 Tape, autoclave indicator, Sigmaware, impregnated to show words Autoclaved
102466 Ethylene glycol, ReagentPlus®, ≥99%
M2128 Thiazolyl Blue Tetrazolium Bromide, 98%
T1503 Trizma® base, Primary Standard and Buffer, ≥99.9% (titration), crystalline

suggested gloves for splash protection

Product #


Add to Cart

Z677531 Lapren latex/chloroprene flock lined gloves, size S
Z677558 Lapren latex/chloroprene flock lined gloves, size M
Z677566 Lapren latex/chloroprene flock lined gloves, size L
Z677574 Lapren latex/chloroprene flock lined gloves, size XL

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?