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D93503 Sigma-Aldrich

Silver diethyldithiocarbamate

ACS reagent, 99%

Synonym: DETC, Diethyldithiocarbamic acid silver salt

  • CAS Number 1470-61-7

  • Linear Formula (C2H5)2NCSSAg

  • Molecular Weight 256.14

  •  Beilstein Registry Number 3718150

  •  EC Number 216-003-7

  •  MDL number MFCD00004929

  •  PubChem Substance ID 24894283



Related Categories Catalysis and Inorganic Chemistry, Chemical Synthesis, Essential Chemicals, Research Essentials, Salts,
grade   ACS reagent
assay   99%
mp   172-175 °C(lit.)
storage temp.   2-8°C



Also used for colorimetric determination of small quantities of arsenic

Reagent for the detection of arsenic and for the introduction of the diethyldithiocarbamato ligand.

Spin trap used in conjunction with Fe2+ to detect NO in brain, kidney, liver, and other tissues. Simultaneous direct measurement of NO* and pO2 has been reported. A copper chelator, it has been used to quantitate copper in biological materials by ESR and is an inhibitor of superoxide dismutase, ascorbate oxidase, and other enzymes.

Biochem/physiol Actions

Inhibits induction of macrophage nitric oxide synthase.


5, 25 g in glass bottle

Price and Availability

Suggested Laboratory Gloves

Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.

Safety & Documentation

Safety Information

GHS07  GHS07
Signal word 
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
WGK Germany 


Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers


Set your institution to view full text papers.

Iron diethyldithiocarbamate as spin trap for nitric oxide detection. Vanin, A.F. Meth. Enzymol. 301, 269, (1999)


In vivo spin trapping of nitric oxide generated in the small intestine, liver, and kidney during the development of endotoxemia: a time-course study. Wallis, G. Shock 6, 274, (1996)


Quantification of copper in biological materials by use of electron spin resonance. Minakata, K. Clin. Chem. 47, 1863, (2001)


Simultaneous measurement of NO(*) and PO2 from tissue by in vivo EPR. James, P.E. Nitric Oxide 3, 292, (1999)


Anal. Chem. 31, 1589, (1959)

Hunjing Baohu, 23, (1991)

Inorg. Chem. 32, 3565, (1993)

Netrin-1 improves post-injury cardiac function in vivo via DCC/NO-dependent preservation of mitochondrial integrity, while attenuating autophagy. Bouhidel JO, Wang P, Siu KL, et al. Biochim. Biophys. Acta 1852(2), 277-89, (2014)


Hepatic protein tyrosine phosphatase 1B (PTP1B) deficiency protects against obesity-induced endothelial dysfunction. Agouni A, Tual-Chalot S, Chalopin M, et al. Biochem. Pharmacol. 92(4), 607-17, (2014)


Superoxide anions in the paraventricular nucleus mediate cardiac sympathetic afferent reflex in insulin resistance rats. Sun HJ, Zhou H, Feng XM, et al. Acta Physiol. (Oxf.) 212(4), 267-82, (2014)


The development and use of an innovative laboratory method for measuring arsenic in drinking water from western Bangladesh. Frisbie SH, Mitchell EJ, Yusuf AZ, et al. Environ. Health Perspect. 113(9), 1196-204, (2005)


Evaluation of two commercial field test kits used for screening of groundwater for arsenic in Northern India. Sankararamakrishnan N, Chauhan D, Nickson RT, et al. Sci. Total Environ. 401(1-3), 162-7, (2008)


Sorption kinetics of arsenic on laterite soil in aqueous medium. Maji SK, Pal A, Pal T, et al. J. Environ. Sci. Health. A. Tox. Hazard. Subst. Environ. Eng. 42(7), 989-96, (2007)


Speciation and analysis of arsenic(III) and arsenic(V) by electrochemical hydride generation spectrophotometric method. Arbab-Zavar MH, Chamsaz M, and Heidari T Anal. Sci. 26(1), 107-10, (2010)


Preconcentration of trace arsenite and arsenate with titanium dioxide nanoparticles and subsequent determination by silver diethyldithiocarbamate spectrophotometric method. Xiao Y, Ling J, Qian S, et al. Water Environ. Res. 79(9), 1015-22, (2007)


Analysis of arsenic in dental cements according to the silverdiethyldithiocarbamate photometric method - ISO 2590. Brune D and Beltesbrekke H Swed. Dent. J. 4(3), 125-8, (1980)


Chem. Abstr. 117, 219549d, (1992)

Beil. 4,IV,391

Aldrich MSDS 1, 667:C / Corp MSDS 1 (1), 1205:D / FT-IR 1 (1), 834:B / FT-IR 2 (1), 1412:C / IR-Spectra (3), 495:F / IR-Spectra (2), 439:C / RegBook 1 (1), 977:J / Sigma FT-IR 1 (2), 461:B / Structure Index 1, 152:D:7

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