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E1271 Sigma-Aldrich

N-Ethylmaleimide

BioXtra, ≥98% (HPLC)

Synonym: NEM

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Properties

Related Categories Apoptosis Inhibitors, Apoptosis and Cell Cycle, Cell Biology, Cell Signaling and Neuroscience, Core Bioreagents,
InChI Key   HDFGOPSGAURCEO-UHFFFAOYSA-N
product line   BioXtra
assay   ≥98% (HPLC)
impurities   ≤0.001% Phosphorus (P)
  ≤0.1% Insoluble matter
ign. residue   ≤0.1%
bp   210 °C(lit.)
mp   43-46 °C(lit.)
solubility   95% ethanol: 50 mg/mL clear to slightly hazy (colorless to faint yellow)
anion traces   chloride (Cl-): ≤0.05%
  sulfate (SO42-): ≤0.05%
cation traces   Al: ≤0.0005%
  Ca: ≤0.0005%
  Cu: ≤0.0005%
  Fe: ≤0.0005%
  K: ≤0.005%
  Mg: ≤0.0005%
  Na: ≤0.005%
  Pb: ≤0.001%
  Zn: ≤0.0005%
storage temp.   2-8°C
Gene Information   human ... SLC6A3(6531), SLC6A4(6532)

Description

Application

Reagent for the covalent modification of cysteine residues in proteins.

Biochem/physiol Actions

Augments currents from native M-channels in sympathetic neurons and acts as an opener for KCNQ2, KCNQ4 and KCNQ5 channels.

Sulfhydryl alkylating agent that inactivates NADP-dependent isocitrate dehydrogenase and many endonucleases.

Packaging

1, 5 g in glass bottle

Price and Availability


Laboratory Gloves

All labs need water
Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN 2928 8(6.1) / PGII
WGK Germany 
3
RTECS 
UX9625000
Flash Point(F) 
163.4 °F
Flash Point(C) 
73 °C

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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