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E3257 Sigma-Aldrich

Ethylene glycol-bis(succinic acid N-hydroxysuccinimide ester)

powder

Synonym: Di(N-succinimidyl) ethylene glycol disuccinate, EGS, Ethylene glycol bis(succinimidyl succinate), Ethylene glycol disuccinate di(N-succinimidyl) ester

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Properties

Related Categories Amine to Amine, Chemical Biology, Chemical Synthesis, Crosslinkers, Crosslinking,
InChI Key   QLHLYJHNOCILIT-UHFFFAOYSA-N
form   powder
solubility   acetic acid: water (1:1): ≤50 mg/mL
  DMF: soluble
storage temp.   2-8°C

Description

Application

Ethylene glycol-bis(succinic acid N-hydroxysuccinimide ester) has been used as a cross-linking agent.

Features and Benefits

The ethylene glycol linkage is cleavable by hydroxylamine.

Packaging

1 g in poly bottle

250 mg in poly bottle

Biochem/physiol Actions

Ethylene glycol-bis(succinic acid N-hydroxysuccinimide ester) is a homobifunctional, cleavable cross-linking reagent. It is mainly coupled to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). The linkage provides a 12-atom spacer.

Price and Availability


Amplified Detection
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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