Synonym: N-Ethyl-N′-(3-dimethylaminopropyl)carbodiimide hydrochloride, EDAC, EDC hydrochloride, WSC hydrochloride
|Related Categories||Crosslinking, Heterobifunctional Cross-Linking Reagents, Protein Modification, Protein Structural Analysis, Proteomics More...|
|solubility||H2O: ≤100 mg/mL|
Water soluble condensing reagent. EDAC is generally utilized as a carboxyl activating agent for amide bonding with primary amines. In addition, it will react with phosphate groups. EDAC has been used in peptide synthesis; crosslinking proteins to nucleic acids; and preparation of immunoconjugates as examples. Typically, EDAC is utilized in the pH range 4.0-6.0 without buffers. In particular, amine and carboxylate buffers should be avoided.
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purum, ≥98.0% (AT)
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Certificate of Analysis
Certificate of Origin
|Precautionary statements||P261-P280-P305 + P351 + P338|
|Personal Protective Equipment||dust mask type N95 (US), Eyeshields, Gloves|
|Hazard Codes (Europe)||Xi|
|Risk Statements (Europe)||37/38-41|
|Safety Statements (Europe)||26-36/37/39|
Synthesis of esters. Dhaon, M.K. J. Org. Chem. 47, 1962, (1982)
Modification of carboxyl groups in proteins, review. Lundblad, R.L., et al. Chemical Reagents for Protein Modification, (1984) 2, 105
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