Synonym: N-Ethyl-N′-(3-dimethylaminopropyl)carbodiimide hydrochloride, EDAC, EDC hydrochloride, WSC hydrochloride
CAS Number 25952-53-8
Empirical Formula (Hill Notation) C8H17N3 · HCl
Molecular Weight 191.70
Beilstein Registry Number 5764110
EC Number 247-361-2
MDL number MFCD00012503
PubChem Substance ID 24894627
Popular Documents: Specification Sheet (PDF)
| Related Categories | Crosslinking, Heterobifunctional Cross-Linking Reagents, Protein Modification, Protein Structural Analysis, Proteomics More... |
| Quality Level | PREMIUM |
| form | crystalline |
| mp | 110-115 °C(lit.) |
| solubility | H2O: ≤100 mg/mL |
| storage temp. | −20°C |
Water soluble condensing reagent. EDAC is generally utilized as a carboxyl activating agent for amide bonding with primary amines. In addition, it will react with phosphate groups. EDAC has been used in peptide synthesis; crosslinking proteins to nucleic acids; and preparation of immunoconjugates as examples. Typically, EDAC is utilized in the pH range 4.0-6.0 without buffers. In particular, amine and carboxylate buffers should be avoided.
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