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E7750 Sigma-Aldrich

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride

commercial grade, powder

Synonym: N-Ethyl-N′-(3-dimethylaminopropyl)carbodiimide hydrochloride, EDAC, EDC hydrochloride, EDC, WSC hydrochloride

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Properties

Related Categories Crosslinking, Heterobifunctional Cross-Linking Reagents, Molecular Biology, Protein Modification, Protein Structural Analysis,
Quality Level   PREMIUM
grade   commercial grade
InChI Key   FPQQSJJWHUJYPU-UHFFFAOYSA-N
form   powder
mp   110-115 °C(lit.)
solubility   H2O: ≤100 mg/mL
storage temp.   −20°C

Description

Frequently Asked Questions

Frequently Asked Questions are available for this Product.

Packaging

1, 5 kg in poly drum

1, 5, 10, 25, 100 g in poly bottle

100 mg in poly bottle

Biochem/physiol Actions

Water soluble condensing reagent. EDAC is generally utilized as a carboxyl activating agent for amide bonding with primary amines. In addition, it will react with phosphate groups. EDAC has been used in peptide synthesis; crosslinking proteins to nucleic acids; and preparation of immunoconjugates as examples. Typically, EDAC is utilized in the pH range 4.0-6.0 without buffers. In particular, amine and carboxylate buffers should be avoided.

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.




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Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
FF2200000
Protocols & Articles

Articles

Graphene Field Effect Transistors for Biological and Chemical Sensors

Victoria Tsai* and Bruce Willner Graphene Frontiers, Philadelphia, PA 19104, USA *Email: victoria@graphenefrontiers.com
Keywords: Adhesion, Chemical vapor deposition, Chromatin immunoprecipitation, Deposition, Drug discovery, Environmental, Evaporation, Ion-exchange chromatography, Nanomaterials, Nanotubes, Semiconductor, Separation

Introduction of Terminal Azide and Alkyne Functionalities in Polymers

“Click” chemistry, and the copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) in particular, is a powerful new synthetic tool in polymer chemistry and material science. Success of the CuAAC in th...
Dr. Joost A. Opsteen
Material Matters 2008, 3.3, 66.
Keywords: Building blocks, Catalysis, Cycloadditions, Esterifications, Materials Science, Nucleophilic substitutions, Polymer science, Polymerization reactions, Radical polymerization, Substitutions, transformation

Peer-Reviewed Papers
15

References

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