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E9508 Sigma-Aldrich

Ethanolamine

≥98%

Synonym: 2-Aminoethanol, 2-Aminoethyl alcohol, ETA, MEA 90, MEA-LCI, MEA, Monoethanolamine

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Properties

Related Categories Allium sativum (Garlic), Biochemicals and Reagents, Biological Buffers, Buffer Convenience Packaging, Buffer Solutions,
Quality Level   PREMIUM
vapor density   2.1 (vs air)
vapor pressure   0.2 mmHg ( 20 °C)
assay   ≥98%
autoignition temp.   1436 °F
expl. lim.   17 %
refractive index   n20/D 1.454(lit.)
pKa (25 °C)   9.5(lit.)
bp   170 °C(lit.)
  69-70 °C/10 mmHg
mp   10-11 °C(lit.)
density   1.012 g/mL at 25 °C(lit.)

Description

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. E9508.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

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Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN 2491 8 / PGIII
WGK Germany 
1
RTECS 
KJ5775000
Flash Point(F) 
186.8 °F
Flash Point(C) 
86 °C

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Determination of Water Content in 2-Aminoethanol Using Karl Fischer Titration

Nitrogen compounds, acid amides and weakly basic amines (heterocyclenes) give no problems. They can be titrated according to the standard procedures. Strongly basic amines alter the pH value and must...
Keywords: Titrations

Peer-Reviewed Papers

References

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Differential 12C-/13C-isotope dansylation labeling and fast liquid chromatography/mass spectrometry for absolute and relative quantification of the metabolome. Guo K and Li L Anal. Chem. 81(10), 3919-32, (2009)

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Lipoproteins secreted by cultured rat hepatocytes contain the antioxidant 1-alk-1-enyl-2-acylglycerophosphoethanolamine. Vance JE Biochim. Biophys. Acta 1045(2), 128-34, (1990)

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Lipophilicity of basic drugs measured by hydrophilic interaction chromatography. Bruno Bard et al J. Med. Chem. 52, 3416-9, (2009)

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Atmospheric chemistry of 2-aminoethanol (MEA): reaction of the NH2(•)CHCH2OH radical with O2. da Silva G J. Phys. Chem. A 116(45), 10980-6, (2012)

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[Antibodies against phospholipids in patients with normal pregnancy]. Karagjozova Zh, Tchernev T, and Baleva M Akush. Ginekol. (Sofiia.) 52(1), 3-6, (2013)

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Synergistic antiproliferative effect of cis-diammine-dichloroplatinum (II) and a new anticancer agent, plasmanyl-(N-acyl)-ethanolamine, an inhibitor of protein kinase C. Mikhaevich IS, Vlasenkova NK, and Gerasimova GK Biomed. Sci. 2(6), 659-64, (1991)

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Spectrophotometric determination of drugs with iodine. Karuna T, et al. J. Sci. Ind. Res. 65(10), 808, (2006)

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Ethanolamine utilization in bacterial pathogens: roles and regulation. Garsin DA Nat. Rev. Microbiol. 8(4), 290-5, (2010)

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FDA-approved drug labeling for the study of drug-induced liver injury. Minjun Chen et al Drug Discov. Today 16, 697-703, (2011)

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Ventricular cerebrospinal fluid concentrations of putative amino acid transmitters in Parkinson's disease and other disorders. Perschak H, Amsler U, Vischer A, et al. Hum. Neurobiol. 6(3), 191-4, (1987)

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Urinary metabolite quantification employing 2D NMR spectroscopy. Gronwald W, Klein MS, Kaspar H, et al. Anal. Chem. 80(23), 9288-97, (2008)

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Analysis of urinary metabolic signatures of early hepatocellular carcinoma recurrence after surgical removal using gas chromatography-mass spectrometry. Ye G, Zhu B, Yao Z, et al. J. Proteome Res. 11(8), 4361-72, (2012)

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Mitochondrially-targeted bacterial phosphatidylethanolamine methyltransferase sustained phosphatidylcholine synthesis of a Saccharomyces cerevisiae Δpem1 Δpem2 double mutant without exogenous choline supply. Kobayashi S, Mizuike A, Horiuchi H, et al. Biochim. Biophys. Acta 1841(9), 1264-71, (2014)

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Omega-3 PUFA ethanolamides DHEA and EPEA induce autophagy through PPARγ activation in MCF-7 breast cancer cells. Rovito D, Giordano C, Vizza D, et al. J. Cell Physiol. 228(6), 1314-22, (2013)

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Developmental changes in choline- and ethanolamine-containing compounds measured with proton-decoupled (31)P MRS in in vivo human brain. Blüml S, Seymour KJ, and Ross BD Magn. Reson. Med. 42(4), 643-54, (1999)

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Treatment of waste metalworking fluid by a hybrid ozone-biological process. Jagadevan S, Graham NJ, and Thompson IP J. Hazard. Mater. 244-245, 394-402, (2013)

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Detection of autosomal dominant polycystic kidney disease by NMR spectroscopic fingerprinting of urine. Gronwald W, Klein MS, Zeltner R, et al. Kidney Int. 79(11), 1244-53, (2011)

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Comparative genomic hybridization analysis shows different epidemiology of chromosomal and plasmid-borne cpe-carrying Clostridium perfringens type A. Lahti P, Lindström M, Somervuo P, et al. PLoS ONE 7(10), e46162, (2012)

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Metabolomic signatures in guinea pigs infected with epidemic-associated W-Beijing strains of Mycobacterium tuberculosis. Somashekar BS, Amin AG, Tripathi P, et al. J. Proteome Res. 11(10), 4873-84, (2012)

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Neurochemical effects of vagus nerve stimulation in humans. Hammond EJ, Uthman BM, Wilder BJ, et al. Brain Res. 583(1-2), 300-3, (1992)

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CuInSe₂ thin-film solar cells with 7.72 % efficiency prepared via direct coating of a metal salts/alcohol-based precursor solution. Ahn S, Son TH, Cho A, et al. ChemSusChem 5(9), 1773-7, (2012)

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A simple gas chromatography method for the analysis of monoethanolamine in air. Gerster FM, Hopf NB, Huynh CK, et al. J. Sep. Sci. 35(17), 2249-55, (2012)

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Amino acids and biogenic amines in cerebrospinal fluid of patients with Parkinson's disease. Engelborghs S, Marescau B, and De Deyn PP Neurochem. Res. 28(8), 1145-50, (2003)

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The genome of Pelobacter carbinolicus reveals surprising metabolic capabilities and physiological features. Aklujkar M, Haveman SA, DiDonato R, et al. BMC Genomics 13, 690, (2012)

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The influences of reaction conditions on magnetic porous pseudo-carbon paste electrode for schistosoma egg antigen detection. Xu L, Du J, and He N J. Nanosci. Nanotechnol. 13(3), 2302-6, (2013)

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Choline and N,N-dimethylethanolamine as direct substrates for methanogens. Watkins AJ, Roussel EG, Webster G, et al. Appl. Environ. Microbiol. 78(23), 8298-303, (2012)

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Evidence that a metabolic microcompartment contains and recycles private cofactor pools. Huseby DL and Roth JR J. Bacteriol. 195(12), 2864-79, (2013)

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Involvement of phospholipase A/acyltransferase-1 in N-acylphosphatidylethanolamine generation. Uyama T, Inoue M, Okamoto Y, et al. Biochim. Biophys. Acta 1831(12), 1690-701, (2013)

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Disease and anatomic specificity of ethanolamine plasmalogen deficiency in Alzheimer's disease brain. Ginsberg L, Rafique S, Xuereb JH, et al. Brain Res. 698(1-2), 223-6, (1995)

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Ethanolamine and choline promote expression of putative and characterized fimbriae in enterohemorrhagic Escherichia coli O157:H7. Gonyar LA and Kendall MM Infect. Immun. 82(1), 193-201, (2014)

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Influence of the CO2 absorbent monoethanolamine on growth and carbon fixation by the green alga Scenedesmus sp. Choi W, Kim G, and Lee K Bioresour. Technol. 120, 295-9, (2012)

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Absorption characteristics of new solvent based on a blend of AMP and 1,8-diamino-p-menthane for CO2 absorption. Lee SS, Mun SM, Choi WJ, et al. J. Environ. Sci. (China) 24(5), 897-902, (2012)

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Ethanolamine utilization in Vibrio alginolyticus. Khatri N, Khatri I, Subramanian S, et al. Biol. Direct 7, 45; discussion 45, (2012)

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Characterisation of the prostaglandin E2-ethanolamide suppression of tumour necrosis factor-α production in human monocytic cells. Brown KL, Davidson J, and Rotondo D Biochim. Biophys. Acta 1831(6), 1098-107, (2013)

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The orally active renin inhibitor A-74273. In vivo and in vitro morpholine ring metabolism in rats, dogs, and humans. Denissen JF, Grabowski BA, Johnson MK, et al. Drug Metab. Dispos. 22(6), 880-8, (1994)

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Synthesis and anti-inflammatory effects of new piperazine and ethanolamine derivatives of H(1)-antihistaminic drugs. Ahmadi A, Khalili M, Nafarie A, et al. Mini Rev. Med. Chem. 12(12), 1282-92, (2012)

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Modification of hydroxypropyl guar gum with ethanolamine. Zhao Y, He J, Han X, et al. Carbohydr. Polym. 90(2), 988-92, (2012)

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Rapid purification method for vitamin A-derived aging pigments A2E and iso-A2E using cation exchange resin. Jee EH, Kim SR, and Jang YP J. Chromatogr. A 1251, 232-5, (2012)

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EutR is a direct regulator of genes that contribute to metabolism and virulence in enterohemorrhagic Escherichia coli O157:H7. Luzader DH, Clark DE, Gonyar LA, et al. J. Bacteriol. 195(21), 4947-53, (2013)

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Biological N removal from wastes generated from amine-based CO2 capture: case monoethanolamine. Hauser I, Colaço AB, Skjæran JA, et al. Appl. Biochem. Biotechnol. 169(4), 1449-58, (2013)

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Anaerobic degradation of carbon capture reclaimer MEA waste. Wang S, Hovland J, and Bakke R Water Sci. Technol. 67(11), 2549-59, (2013)

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Effect of low temperature upon vitality of Saccharomyces cerevisiae phospholipid mutants. Redón M, Borrull A, López M, et al. Yeast 29(10), 443-52, (2012)

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Use of ethanolamine for sample stacking in capillary electrophoresis. Louwagie M, Rabilloud T, and Garin J Electrophoresis 19(14), 2440-4, (1998)

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Quantification of canavanine, 2-aminoethanol, and cyanamide in Aphis craccivora and its host plants, Robinia pseudoacacia and Vicia angustifolia: effects of these compounds on larval survivorship of Harmonia axyridis. Kamo T, Tokuoka Y, and Miyazaki M J. Chem. Ecol. 38(12), 1552-60, (2012)

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Determination method for mono- and diethanolamine in workplace air by high-performance liquid chromatography. Takeuchi A, Kitade T, Jukurogi A, et al. J. Occup. Health 54(4), 340-3, (2012)

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Levels of ethanolamine intermediates in the human and rat visual system structures: comparison with neural tissues of a lower vertebrate (Mustelus canis) and an invertebrate (Loligo pealei). Alberghina M, Giacchetto A, and Cavallaro N Neurochem. Int. 22(1), 45-51, (1993)

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3-D-QSAR and docking studies on the neuronal choline transporter. Werner J Geldenhuys et al Bioorg. Med. Chem. Lett. 20, 4870-7, (2010)

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Letter: Mass spectrometric approach of high pH- and copper-induced glutathione oxidation. Drochioiu G, Ion L, Ciobanu C, et al. Eur. J. Mass Spectrom. (Chichester, Eng.) 19(1), 71-5, (2013)

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Body composition in patients with classical homocystinuria: body mass relates to homocysteine and choline metabolism. Poloni S, Leistner-Segal S, Bandeira IC, et al. Gene 546(2), 443-7, (2014)

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Chromatographic separation of plasmalogenic, alkyl-acyl, and diacyl forms of ethanolamine glycerophosphatides. Renkonen O J. Lipid Res. 9(1), 34-9, (1968)

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Merck 14,3727

Beil. 4,IV,1406

Fieser 1,357 / Fieser 2,189 / Fieser 4,222 / Fieser 16,162

Aldrich MSDS 1, 863:C / Corp MSDS 1 (1), 1547:B / FT-IR 1 (1), 334:A / FT-IR 2 (1), 525:D / FT-NMR 1 (1), 535:B / IR-Spectra (2), 177:H / IR-Spectra (3), 197:B / NMR-Reference 2 (1), 291:B / RegBook 1 (1), 361:F / Sax 6, 1956 / Structure Index 1, 50:C:6 / Vapor Phase 3, 423:D

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