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F6377 Sigma-Aldrich

Fluorescein sodium salt

used as fluorescent tracer

Synonym: Acid Yellow 73, D&C;Yellow No. 8, NaFl, NaFluo, Sodium fluorescein, Uranine

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Properties

Related Categories Cell Biology, E-F, Hematology and Histology, Stains & Dyes, A to Z, Stains and Dyes More...
InChI Key   RGPLGPBQJOQFJS-UHFFFAOYSA-L
form   powder
solubility   H2O: 1 mg/mL
fluorescence   λex 460 nm; λem 515 nm(lit.)

Description

Packaging

100, 500 g in glass bottle

Application

Fluorescein sodium salt has been used as a solute to study microvessel permeability. It has been used as a test molecule to study blood barrier penetration.

Water soluble fluorescent dye used in permeability and vascular perfusion studies due to its small molecular radius. Sodium fluorescein is used as a fluorescent tracer to study blood-brain barrier (BBB) and blood-spinal cord barrier (BSCB) permeability in rodent models. The dye was used as a probe substrate in the study of organic anion transporting polypeptide (OATP) mediated drug transport in hepatocytes. Sodium fluorescein was also used to monitor in situ solute transportation into bone through fluorescence recovery after photobleaching (FRAP).

General description

Fluorescein is a xanthene dye and is a common labeling agent in biology.

Price and Availability


Tissue Diagnostics

All labs need water

Biomedical Applications
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
LM5425000

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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