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F7002 Sigma-Aldrich

Iron(II) sulfate heptahydrate

ReagentPlus®, ≥99%

Synonym: Ferrous sulfate heptahydrate

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Properties

Related Categories Essential Chemicals, Iron Salts, Molecular Biology, Phosphorylation Analysis, Post-Translational Modification,
grade   ReagentPlus®
vapor pressure   14.6 mmHg ( 25 °C)
assay   ≥99%
density   1.898 g/mL at 25 °C(lit.)

Description

Packaging

1 kg in poly bottle

250, 500 g in poly bottle

Legal Information

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Price and Availability

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Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.



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Ultra-high Purity Salts

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puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., 99.0-103.4% (manganometric)

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
RTECS 
NO8510000

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Determination of Water Content in Iron(II) sulfate-7-hydrate Using Karl Fischer Titration

Adherent moisture in salts can be easily determined. It is best to choose a working medium which will prevent the salt from dissolving, e.g. a Methanol-Chloroform mixture with an excess of Chloroform...
Keywords: Crystallization, Titrations

Protocols

Enzymatic Activity of Glucose-6-Phosphatase [EC 3.1.3.9]

Replaces enzyme assay procedure SSGLUC02. Document number and formatting changed to reflect current numbering and formatting guidelines. The procedure was modified to include a standard curve that re...
Keywords: Enzyme activity, Enzymology

Enzymatic Assay of 5’-Nucleotidase

1. OBJECTIVE To standardize a procedure for determining the enzymatic activity of 5’-Nucleotidase.
Keywords: Chromatography, Enzyme activity

Peer-Reviewed Papers

References

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Iron bioavailability from a lipid-based complementary food fortificant mixed with millet porridge can be optimized by adding phytase and ascorbic acid but not by using a mixture of ferrous sulfate and sodium iron EDTA. Cercamondi CI, Egli IM, Mitchikpe E, et al. J. Nutr. 143(8), 1233-9, (2013)

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Protective effects of pulmonary epithelial lining fluid on oxidative stress and DNA single-strand breaks caused by ultrafine carbon black, ferrous sulphate and organic extract of diesel exhaust particles. Chuang HC, Cheng YL, Lei YC, et al. Toxicol. Appl. Pharmacol. 266(3), 329-34, (2013)

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Application of the Fenton process in the elimination of helminth eggs. Escobar-Megchún SI, Nájera-Aguilar HA, González-Hilerio M, et al. J. Water Health 12(4), 722-6, (2014)

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A nanoparticulate ferritin-core mimetic is well taken up by HuTu 80 duodenal cells and its absorption in mice is regulated by body iron. Latunde-Dada GO, Pereira DI, Tempest B, et al. J. Nutr. 144(12), 1896-902, (2014)

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Effects of iron on the pharmacokinetics of paracetamol in saliva. Issa MM, Nejem RM, and Shanab AA Pak. J. Biol. Sci. 16(24), 2050-3, (2013)

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[Effect of growth factors and some microelements on biosurfactant synthesis of Acinetobacter calcoaceticus IMV B-7241]. Pirog TP, Shevchuk TA, Mashchenko OIu, et al. Mikrobiol. Z. 75(5), 18-26, (2013)

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[Influence of transition metal compounds on superoxide dismutase activity of sulfur reducing Desulfuromonas acetoxidans bacteria]. Vasyliv OM and Hnatush SO Mikrobiol. Z. 75(2), 37-44, (2013)

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Managing severe anemia when the patient is a Jehovah's Witness. Lynn S and McDaniel J JAAPA 26(4), 24, 27-9, (2013)

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Effect of chemical activation of 10% carbamide peroxide gel in tooth bleaching. Batista GR, Arantes PT, Attin T, et al. Eur. J. Esthet. Dent. 8(1), 104-17, (2013)

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A randomized, double-blind clinical study on the safety and tolerability of an iron multi-amino acid chelate preparation in premenopausal women. Fouad GT, Evans M, Sharma P, et al. J. Diet. Suppl. 10(1), 17-28, (2013)

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A misguided 'pill in the pocket' approach with flecainide leading to cardiac arrest. Kiblboeck D, Braeuer-Mocker M, Siostrzonek P, et al. BMJ Case Rep. 2012, doi:10.1136/bcr-2012-006868, (2012)

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Tolerability of different oral iron supplements: a systematic review. Cancelo-Hidalgo MJ, Castelo-Branco C, Palacios S, et al. Curr. Med. Res. Opin. 29(4), 291-303, (2013)

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Impacts of operating parameters on oxidation-reduction potential and pretreatment efficacy in the pretreatment of printing and dyeing wastewater by Fenton process. Wu H and Wang S J. Hazard. Mater. 243, 86-94, (2012)

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Hepcidin levels predict nonresponsiveness to oral iron therapy in patients with iron deficiency anemia. Bregman DB, Morris D, Koch TA, et al. Am. J. Hematol. 88(2), 97-101, (2013)

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Influence of rutin, FeSO4, Tween 80, aspartate and complex vitamins on synthesis of fungal exopolysaccharide. Ma XK, Zhang H, and Fam H Carbohydr. Polym. 92(2), 1188-96, (2013)

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Preparation of entangled nanocellulose fibers from APMP and its magnetic functional property as matrix. Li W, Zhao X, and Liu S Carbohydr. Polym. 94(1), 278-85, (2013)

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Preference and drinking behavior of lactating dairy cows offered water with different concentrations, valences, and sources of iron. Genther ON and Beede DK J. Dairy Sci. 96(2), 1164-76, (2013)

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Microcytic anemia. DeLoughery TG N. Engl. J. Med. 371(14), 1324-31, (2014)

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Cluster-randomised trial of the impact of school-based deworming and iron supplementation on the cognitive abilities of schoolchildren in Sri Lanka's plantation sector. Ebenezer R, Gunawardena K, Kumarendran B, et al. Trop. Med. Int. Health 18(8), 942-51, (2013)

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Inhibition of bacterial oxidation of ferrous iron by lead nitrate in sulfate-rich systems. Wang H, Gong L, Cravotta CA, et al. J. Hazard. Mater. 244-245, 718-25, (2013)

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Two-photon microscopy and fluorescence lifetime imaging of retinal pigment epithelial cells under oxidative stress. Miura Y, Huettmann G, Orzekowsky-Schroeder R, et al. Invest. Ophthalmol. Vis. Sci. 54(5), 3366-77, (2013)

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Effect of ferrous sulfate fortification in germinated brown rice on seed iron concentration and bioavailability. Wei Y, Shohag MJ, Ying F, et al. Food Chem. 138(2-3), 1952-8, (2013)

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Marginally excessive iron loading transiently blocks mucosal iron uptake in iron-deficient rats. Shinoda S, Yoshizawa S, Nozaki E, et al. Am. J. Physiol. Gastrointest. Liver Physiol. 307(1), G89-97, (2014)

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Changes of excitation/emission matrixes of wastewater caused by Fenton- and Fenton-like treatment and their associations with the generation of hydroxyl radicals, oxidation of effluent organic matter and degradation of trace-level organic pollutants. Li W, Nanaboina V, Zhou Q, et al. J. Hazard. Mater. 244-245, 698-708, (2013)

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Multiple micronutrient supplementation reduces anemia and anxiety in rural China's elementary school children. Zhang L, Kleiman-Weiner M, Luo R, et al. J. Nutr. 143(5), 640-7, (2013)

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Treatment of textile dye wastewaters using ferrous sulphate in a chemical coagulation/flocculation process. Rodrigues CS, Madeira LM, and Boaventura RA Environ. Technol. 34(5-8), 719-29, (2013)

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A modified ferrous oxidation-xylenol orange assay for lipoxygenase activity in rice grains. Timabud T, Sanitchon J, and Pongdontri P Food Chem. 141(3), 2405-11, (2013)

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Fortification of wheat flour and maize meal with different iron compounds: results of a series of baking trials. Randall P, Johnson Q, and Verster A Food Nutr. Bull. 33(4 Suppl), S344-59, (2012)

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Decreasing effect and mechanism of FeSO4 seed particles on secondary organic aerosol in α-pinene photooxidation. Chu B, Liu Y, Li J, et al. Environ. Pollut. 193, 88-93, (2014)

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Nucleoside 5'-phosphorothioate derivatives are highly effective neuroprotectants. Danino O, Giladi N, Grossman S, et al. Biochem. Pharmacol. 88(3), 384-92, (2014)

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Zinc supplementation sustained normative neurodevelopment in a randomized, controlled trial of Peruvian infants aged 6-18 months. Colombo J, Zavaleta N, Kannass KN, et al. J. Nutr. 144(8), 1298-305, (2014)

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Evaluation of lipid peroxidation and antioxidant system in healthy iron-replete infants receiving iron prophylaxis. Hacihamdioglu DÖ, Kurekci AE, Gursel O, et al. Nutrition 29(1), 138-42, (2013)

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Fortifying baladi bread in Egypt: reaching more than 50 million people through the subsidy program. Elhakim N, Laillou A, El Nakeeb A, et al. Food Nutr. Bull. 33(4 Suppl), S260-71, (2012)

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Ferrous sulfate (Fe2+) had a faster effect than did ferric polymaltose (Fe3+) on increased oxidant status in children with iron-deficiency anemia. Aycicek A, Koc A, Oymak Y, et al. J. Pediatr. Hematol. Oncol. 36(1), 57-61, (2014)

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Alpha-mangostin induces changes in glutathione levels associated with glutathione peroxidase activity in rat brain synaptosomes. Márquez-Valadez B, Maldonado PD, Galván-Arzate S, et al. Nutr. Neurosci. 15(5), 13-9, (2012)

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The effect of copper(II), iron(II) sulphate, and vitamin C combinations on the weak antimicrobial activity of (+)-catechin against Staphylococcus aureus and other microbes. Holloway AC, Mueller-Harvey I, Gould SW, et al. Metallomics 4(12), 1280-6, (2012)

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Modulation of the shape and speed of a chemical wave in an unstirred Belousov-Zhabotinsky reaction by a rotating magnet. Okano H and Kitahata H Bioelectromagnetics 34(3), 220-30, (2013)

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Fortification of staple cereal flours with iron and other micronutrients: cost implications of following World Health Organization-endorsed recommendations. Aaron GJ, Laillou A, Wolfson J, et al. Food Nutr. Bull. 33(4 Suppl), S336-43, (2012)

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Iron autointoxication in a 16-year-old girl: a protective role for hepcidin? Simonse E, Valk-Swinkels CG, van 't Veer NE, et al. Ann. Clin. Biochem. 50(Pt 1), 76-9, (2013)

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Merck 14,4057

Fieser 1,393 / Fieser 4,237 / Fieser 5,308 / Fieser 11,276

Corp MSDS 1 (1), 2014:D / RegBook 1 (3), 3443:H / Sax 6, 1416 / Sigma FT-IR 1 (2), 1023:C

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