|Related Categories||Bioactive Small Molecules, Biochemicals and Reagents, Calcium Probes, Calcium Signaling Research Tools, Cell Biology,|
|fluorescence||λex 330 nm; λem 450 nm (with Calcium)|
|λex 356 nm; λem 478 nm in methanol|
Cell permeable fluorescent probe for Ca2+; lower affinity than FURA 2; gives a large shift in fluorescent emission from 482 nm to 398 nm upon Ca2+ binding.
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suitable for fluorescence, ~70%
BioReagent, suitable for fluorescence, ≥95.0% (HPLC)
powder, ≥98% (HPLC)
In 1998 R.F. Furchgott, L.J. Ignarro, and F. Murad received the Nobel Prize in Physiology and Medicine for their discoveries concerning nitric oxide as a signaling molecule in the cardiovascular syst...
BioFiles 2011, 6.3, 23.
Keywords: Biochemistry, Biological processes, Cancer, Cardiovascular, Central Nervous System, Diseases, Extinction coefficient, Indicators, Inflammation, Microscopy, Neurotransmission, Sol-gel
Calcium sequestration by isolated sarcoplasmic reticulum: real-time monitoring using ratiometric dual-emission spectrofluorometry and the fluorescent calcium-binding dye indo-1. O'Brien Mol. Cell Biochem. 94, 113, (1990)
Differential inhibition by the Rho kinase inhibitor Y-27632 of the increases in contractility and Ca2+ transients induced by endothelin-1 in rabbit ventricular myocytes. Chu L, Norota I, and Endoh M Naunyn Schmiedebergs Arch. Pharmacol. 371(3), 185-94, (2005)
Differential aspects in ratio measurements of [Ca(2+)](i) relaxation in cardiomyocyte contraction following various drug treatments. Fixler D, Tirosh R, Zinman T, et al. Cell Calcium 31(6), 279-87, (2002)
Pharmacological analysis by HOE642 and KB-R9032 of the role of Na(+)/H(+) exchange in the endothelin-1-induced Ca(2+) signalling in rabbit ventricular myocytes. Wang H, Sakurai K, and Endoh M Br. J. Pharmacol. 131(3), 638-44, (2000)
The alpha9 nicotinic acetylcholine receptor shares pharmacological properties with type A gamma-aminobutyric acid, glycine, and type 3 serotonin receptors. Rothlin CV, Katz E, Verbitsky M, et al. Mol. Pharmacol. 55(2), 248-54, (1999)
Modulation of the kinetics of inositol 1,4,5-trisphosphate-induced [Ca2+]i oscillations by calcium entry in pituitary gonadotrophs. Kukuljan M, Vergara L, and Stojilkovic SS Biophys. J. 72(2 Pt 1), 698-707, (1997)
Effects of endothelin-1 on [Ca2+]i-shortening trajectory and Ca2+ sensitivity in rabbit single ventricular cardiomyocytes loaded with indo-1/AM: comparison with the effects of phenylephrine and angiotensin II. Fujita S and Endoh M J. Card. Fail. 2(4 Suppl), S45-57, (1996)
Testosterone inhibits the prostaglandin F2alpha-mediated increase in intracellular calcium in A7r5 aortic smooth muscle cells: evidence of an antagonistic action upon store-operated calcium channels. Jones RD, Ruban LN, Morton IE, et al. J. Endocrinol. 178(3), 381-93, (2003)
Role of Na+/Ca2+ exchange in endothelin-1-induced increases in Ca2+ transient and contractility in rabbit ventricular myocytes: pharmacological analysis with KB-R7943. Yang HT, Sakurai K, Sugawara H, et al. Br. J. Pharmacol. 126(8), 1785-95, (1999)
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