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P8721 Sigma-Aldrich

Penicillin G potassium salt

meets USP testing specifications, powder

Synonym: Benzylpenicillin potassium salt

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Properties

Related Categories Analytical/Chromatography, Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics N-S,
InChI Key   IYNDLOXRXUOGIU-LQDWTQKMSA-M
form   powder
potency   1440-1680 units per mg
solubility   H2O: 100 mg/mL
suitability   meets USP testing specifications
Mode of action   cell wall synthesis | interferes
antibiotic activity spectrum   Gram-positive bacteria

Description

Application

Penicillin G is a narrow spectrum antibiotic derived from Streptococcus pneumoniae. It is the drug of choice for groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridians group streptococci, and non-penicillinase producing staphylococcus. The potassium salt has been used to study murosomes of staphylococci and the penicillin-induced lysis of Streptococcus mutans.

Biochem/physiol Actions

Mode of Action: Penicillin G acts by inhibiting cell wall synthesis through binding to penicillin binding proteins (PBPs), inhibiting peptidoglycan chain cross-linking.

Antimicrobial spectrum: This product is active against gram-positive and gram-negative bacteria.

Caution

Solutions should be filter sterilized and stored at 2-8°C for 1 week or at -20°C for more lengthy periods. Solutions are stable at 37°C for 3 days. The sodium salt is soluble in H2O at 100 mg/mL.

Packaging

10mu,25mu,100mu

Other Notes

Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place

Price and Availability

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
XH9700000

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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