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PHR1023 Sigma-Aldrich

Theophylline

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: 1,3-Dimethylxanthine, 2,6-Dihydroxy-1,3-dimethylpurine, 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione

  • CAS Number 58-55-9

  • Empirical Formula (Hill Notation) C7H8N4O2

  • Molecular Weight 180.16

  •  Beilstein Registry Number 13463

  •  EC Number 200-385-7

  •  MDL number MFCD00079619

  •  PubChem Substance ID 329823053

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Properties

Related Categories Additional Standards, Alphabetical Index of Phytochemical Standards, Analytical Standards, Analytical/Chromatography, Caffeine Impurities,
grade   certified reference material
  pharmaceutical secondary standard
InChI Key   ZFXYFBGIUFBOJW-UHFFFAOYSA-N
form   neat
format   neat
pharmacopeia traceability   traceable to BP 327
  traceable to PhEur T080000
  traceable to USP 1653004

Description

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Biochem/physiol Actions

Phosphodiesterase inhibitor; diuretic; cardiac stimulant; muscle relaxant; asthma medication.

General description

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards

Other Notes

This product was designed, produced and verified for accuracy and stability in accordance with ISO/IEC 17025:2005 (AClass Cert AT-1467), ISO GUIDES 34:2009 (AClass Cert AR-1470).

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA7171 in the slot below. This is an example certificate only and may not be the lot that you receive.

Price and Availability

Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
1
RTECS 
XH3850000
Protocols & Articles

Articles

HPLC Analysis of Bronchodilators Theophylline and Other Caffeine Metabolites in Serum on Discovery® RP-AmideC16 after SPE using Discovery® DSC-18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Bronchodilators Theophylline and Other Caffeine Metabolites in Serum on Discovery® RP-AmideC16 after SPE using Discovery® DSC-18
Keywords: Calorimetry, Chromatography, Clinical, High performance liquid chromatography, Pharmaceutical, Sample preparations, Solid phase extractions

HPLC Analysis of Caffeine Metabolites and Analogs on Discovery® C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Caffeine Metabolites and Analogs on Discovery® C18
Keywords: Chromatography, Clinical, High performance liquid chromatography

HPLC Analysis of Xanthines on Purospher®STAR RP-18 endcapped

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Xanthines on Purospher®STAR RP-18 endcapped
Keywords: Chromatography, Clinical, High performance liquid chromatography, Pharmaceutical, Separation

TLC Analysis of Expectorants on HPTLC Silica Gel 60 RP-18 WF254s

From our library of Articles, Sigma-Aldrich presents TLC Analysis of Expectorants on HPTLC Silica Gel 60 RP-18 WF254s
Keywords: Chromatography, Pharmaceutical, Thin layer chromatography

Peer-Reviewed Papers
15

References

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