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Q0132 Sigma-Aldrich

Quinine sulfate

meets USP testing specifications, monograph mol wt. 782.94 ((C20H24N2O2)2 . H2SO4 . 2H2O)

Synonym: Quinine hemisulfate salt monohydrate, Quinine sulfate (2:1) (salt) dihydrate

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Properties

Related Categories Alkaloid, Antibiotics, Antibiotics A to Z, Antibiotics N-S, Antiparasitic / Antiprotozoal / Anthelminthic,
InChI Key   ZHNFLHYOFXQIOW-LPYZJUEESA-N
mol wt   monograph mol wt. 782.94 ((C20H24N2O2)2 . H2SO4 . 2H2O)
mp   ~225 °C (dec.)(lit.)
suitability   meets USP testing specifications

Description

Application

Use to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites, the toxicity of heme (FP)-complexes and to inhibit mitochondrial ATP-regulated potassium channel.

Packaging

10, 25, 50 g in glass bottle

Biochem/physiol Actions

Potassium channel blocker. Antimalarial, anticholinergic, antihypertensive, and hypoglycemic agent; alkaloid originally isolated from the Cinchona family of South American trees. Inhibits mitochondrial ATP-regulated potassium channel. Used to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.

Price and Availability

Suggested Laboratory Gloves


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Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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