S2002 Sigma-Aldrich

Sodium azide

ReagentPlus®, ≥99.5%

Synonym: Hydrazoic acid sodium salt, NSC 3072



Frequently Asked Questions

Frequently Asked Questions are available for this Product.


2 kg in poly bottle

25 kg in poly drum

5, 25, 100, 500 g in poly bottle


Baylis-Hillman acetates such as ethyl 2-(acetoxyphenylmethyl)acrylate can undergo nucleophilic displacement by sodium azide in aqueous medium to form ethyl (E)-2-azidomethyl-3-phenylpropenoate.

Catalyst for:
• Oxidative decarboxylation
• Michael addition reactions

Reagent for synthesis of
• Blue fluorescent copolymers
• Metal phosphonates
• Arenes via aminations

Involved in regioselective synthesis of prianosin B

General description

Sodium azide is commonly used as a bacteriostatic preservative for biological samples and also as a source to generate gas in automobile airbags. It is also a metabolic inhibitor, which inhibits oxidative phosphorylation.

Legal Information

ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

Price and Availability

Laboratory Gloves

Biomedical Applications
Safety & Documentation

Safety Information

Signal word 
Hazard statements 
Target organs 
Supplemental Hazard Statements 
Contact with acids liberates very toxic gas.
UN 1687 6.1 / PGII
WGK Germany 


Certificate of Analysis

Certificate of Origin

Frequently Asked Questions

What concentrations of Product S2002, Sodium azide, are used as a preservative?
Typical concentrations for use are from 0.02 % to 0.1 %.  To view this information on the Product Information Sheet please click on the following link:
How can I determine the concentration of sodium azide in solution?
Sodium azide forms a 3,5-dinitrobenzoyl derivative that can be quantified by liquid chromatography.  This method is reported in the Journal of Chromatography, 5, 597 (1982).
Are there any hazards associated with the disposal of Product S2002, Sodium azide?
Sodium azide can form metal azides.  If you have metal pipes for your plumbing, you should not dispose of solutions down them.  To view this information on the Material Safety Data Sheet please click on the following link. The MSDS link is located under Related Information:
How stable are solutions of Product S2002, Sodium azide?
At a neutral pH sodium azide solutions are fairly stable.  Under acidic conditions it is converted to hydrazoic acid, a volatile gas.  To view this information on the Product Information Sheet please click on the following link:
How does Product S2002, Sodium azide, inhibit certain metalloenzymes?
The mechanism of sodium azide inhibition may be due to metal ion complexation and displacement from the enzyme.  To view this information on the Product Information Sheet please click on the following link:
Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis. These documents are located on the product detail page under Useful Links & Tools. Click on the following link to search for a Certificate of Analysis. Please click the following link to see the details on our Product Dating Information.
How do I get lot-specific information or a Certificate of Analysis?
A Certificate of Analysis is available by lot number and can be obtained through our Advanced Search Option:
How do I find price and availability?
There are several ways to find pricing and availability for our products.  Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers. 
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS. To access the shipping information for this material, use the link on the product detail page for the product, or search here. 
My question is not addressed here, how can I contact Technical Service for assistance?
Use the option to the right to "Ask a Question" by email of a Technical Service Scientist.
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