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S5016 Sigma-Aldrich

Sucrose

ACS reagent

Synonym: α-D-Glc-(1→2)-β-D-Fru, α-D-Glucopyranosyl β-D-fructofuranoside, β-D-Fructofuranosyl-α-D-glucopyranoside, D(+)-Saccharose, Sugar

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Properties

Related Categories Biochemicals and Reagents, Carbohydrate Chemistry, Carbohydrate Derivatives, Carbohydrates, Carbohydrates A to Z,
Quality Level   PREMIUM
grade   ACS reagent
optical activity   [α]25/D +66.3 to +66.8°(lit.)
impurities   ≤0.0008 meq/g Titratable acid
  ≤0.005% Insoluble matter
  ≤0.05% Invert sugar
ign. residue   ≤0.01%
loss   ≤0.03% loss on drying, 105°C
mp   185-187 °C(lit.)
anion traces   chloride (Cl-): ≤0.005%
  sulfate, sulfite (as SO42-): ≤0.005%
cation traces   Fe: ≤5 ppm
  heavy metals (as Pb): ≤5 ppm
Featured Industry   Agriculture

Description

Packaging

1 kg in poly bottle

2.5 kg in poly drum

25, 500 g in poly bottle

Price and Availability

Suggested Laboratory Gloves


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Safety & Documentation

Safety Information

WGK Germany 
2
RTECS 
WN6500000

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Determination of Water Content in D(+)-Glucose monohydrate Using Karl Fischer Titration

Carbohydrates comprise diverse compounds, mono-, di- and polysaccharides. Mono- and disaccharides dissolve in Methanol or solvent mixtures and can thus be titrated. If only adherent water is to be de...
Keywords: Pharmaceutical, Titrations

Determination of Water Content in D(+)-Sucrose (adh. water) Using Karl Fischer Titration

Carbohydrates comprise diverse compounds, mono-, di- and polysaccharides. Mono- and disaccharides dissolve in Methanol or solvent mixtures and can thus be titrated. If only adherent water is to be de...
Keywords: Titrations

Determination of Water Content in D(+)-Sucrose (total water) Using Karl Fischer Titration

Carbohydrates comprise diverse compounds, mono-, di- and polysaccharides. Mono- and disaccharides dissolve in Methanol or solvent mixtures and can thus be titrated. If only adherent water is to be de...
Keywords: Titrations

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Peer-Reviewed Papers

References

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A bacterial glucanotransferase can replace the complex maltose metabolism required for starch to sucrose conversion in leaves at night. Ruzanski C, Smirnova J, Rejzek M, et al. J. Biol. Chem. 288(40), 28581-98, (2013)

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Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression. Sreekumar A, Poisson LM, Rajendiran TM, et al. Nature 457(7231), 910-4, (2009)

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Optogenetic excitation of central amygdala amplifies and narrows incentive motivation to pursue one reward above another. Robinson MJ, Warlow SM, and Berridge KC J. Neurosci. 34(50), 16567-80, (2014)

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Transcriptome and metabolome analyses of sugar and organic acid metabolism in Ponkan (Citrus reticulata) fruit during fruit maturation. Lin Q, Wang C, Dong W, et al. Gene 554(1), 64-74, (2015)

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Human N-methyl D-aspartate receptor antibodies alter memory and behaviour in mice. Planagumà J, Leypoldt F, Mannara F, et al. Brain 138(Pt 1), 94-109, (2015)

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Fructose- and glucose-conditioned preferences in FVB mice: strain differences in post-oral sugar appetition. Sclafani A, Zukerman S, and Ackroff K Am. J. Physiol. Regul. Integr. Comp. Physiol. 307(12), R1448-57, (2014)

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Sucrose consumption test reveals pharmacoresistant depression-associated behavior in two mouse models of temporal lobe epilepsy. Klein S, Bankstahl JP, Löscher W, et al. Exp. Neurol. 263, 263-71, (2015)

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Proton-associated sucrose transport of mammalian solute carrier family 45: an analysis in Saccharomyces cerevisiae. Bartölke R, Heinisch JJ, Wieczorek H, et al. Biochem. J. 464(2), 193-201, (2014)

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Pnpla3I148M knockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis. Smagris E, BasuRay S, Li J, et al. Hepatology 61(1), 108-18, (2015)

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Study of the bioremediation of atrazine under variable carbon and nitrogen sources by mixed bacterial consortium isolated from corn field soil in Fars province of Iran. Dehghani M, Nasseri S, and Hashemi H J. Environ. Public Health 2013, 973165, (2013)

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Sucrose signaling in plants: a world yet to be explored. Tognetti JA, Pontis HG, and Martínez-Noël GM Plant Signal Behav. 8(3), e23316, (2013)

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Biomarkers of small intestinal mucosal damage induced by chemotherapy: an emerging role for the 13C sucrose breath test. Wardill HR, Bowen JM, and Gibson RJ J. Support. Oncol. 11(2), 61-7, (2013)

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The analgesic properties of intraoral sucrose: an integrative review. Hatfield LA, Chang K, Bittle M, et al. Adv. Neonatal Care 11(2), 83-92; quiz 93-4, (2011)

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SnRK2 acts within an intricate network that links sucrose metabolic and stress signaling in wheat. Zhang H, Mao X, and Jing R Plant Signal Behav. 6(5), 652-4, (2011)

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Membrane-transport systems for sucrose in relation to whole-plant carbon partitioning. Ayre BG Mol. Plant 4(3), 377-94, (2011)

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Receptor for activated C-kinase (RACK1) homolog Cpc2 facilitates the general amino acid control response through Gcn2 kinase in fission yeast. Tarumoto Y, Kanoh J, and Ishikawa F J. Biol. Chem. 288(26), 19260-8, (2013)

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Sucrose for analgesia in newborn infants undergoing painful procedures. Stevens B, Yamada J, Lee GY, et al. Cochrane Database Syst. Rev. 1, CD001069, (2013)

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Critical role of the interleukin-17/interleukin-17 receptor axis in regulating host susceptibility to respiratory infection with Chlamydia species. Zhou X Infect. Immun. 77(11), 5059-70, (2009)

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Acute hippocampal brain-derived neurotrophic factor restores motivational and forced swim performance after corticosterone. Shannon L. Gourley et al Biol. Psychiatry 64, 884-90, (2008)

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Mosquitoes smell and avoid the insect repellent DEET. Syed Z Proc. Natl. Acad. Sci. U. S. A. 105(36), 13598-603, (2008)

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Artificial sweeteners induce glucose intolerance by altering the gut microbiota. Suez J, Korem T, Zeevi D, et al. Nature, doi:10.1038/nature13793, (2014)

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Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Denis Fourches et al Chem. Res. Toxicol. 23, 171-83, (2010)

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Sugars and risk of mortality in the NIH-AARP Diet and Health Study. Tasevska N, Park Y, Jiao L, et al. Am. J. Clin. Nutr. 99(5), 1077-88, (2014)

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Functional role of oligomerization for bacterial and plant SWEET sugar transporter family. Xuan YH, Hu YB, Chen LQ, et al. Proc. Natl. Acad. Sci. U. S. A. 110(39), E3685-94, (2013)

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Gustation assessment using the NIH Toolbox. Coldwell SE, Mennella JA, Duffy VB, et al. Neurology 80(11 Suppl 3), S20-4, (2013)

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The lipid-sensor candidates CD36 and GPR120 are differentially regulated by dietary lipids in mouse taste buds: impact on spontaneous fat preference. Martin C, Passilly-Degrace P, Gaillard D, et al. PLoS ONE 6(8), e24014, (2011)

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Urinary sucrose and fructose as biomarkers for sugar consumption. Tasevska N, Runswick SA, McTaggart A, et al. Cancer Epidemiol. Biomarkers Prev. 14(5), 1287-94, (2005)

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Purification of exosome-like vesicles from urine. Chen CY, Hogan MC, and Ward CJ Meth. Enzymol. 524, 225-41, (2013)

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Detection of autosomal dominant polycystic kidney disease by NMR spectroscopic fingerprinting of urine. Gronwald W, Klein MS, Zeltner R, et al. Kidney Int. 79(11), 1244-53, (2011)

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SWEET as sugar: new sucrose effluxers in plants. Baker RF, Leach KA, and Braun DM Mol. Plant 5(4), 766-8, (2012)

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Prevention of hepatic steatosis and hepatic insulin resistance by knockdown of cAMP response element-binding protein. Derek M. Erion et al Cell Metab. 10, 499-506, (2009)

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The combined use of sucrose and nonnutritive sucking for procedural pain in both term and preterm neonates: an integrative review of the literature. Naughton KA Adv. Neonatal Care 13(1), 9-19; quiz 20-1, (2013)

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Photosynthetic entrainment of the Arabidopsis thaliana circadian clock. Haydon MJ, Mielczarek O, Robertson FC, et al. Nature 502(7473), 689-92, (2013)

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SUBPOL: a novel SUcrose-Based Polymer support for solid-phase peptide synthesis and affinity chromatography applications. Poschalko A, Rohr T, Gruber H, et al. J. Am. Chem. Soc. 125(44), 13415-26, (2003)

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Sucrose esters as natural surfactants in drug delivery systems--a mini-review. Szűts A and Szabó-Révész P Int. J. Pharm. 433(1-2), 1-9, (2012)

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Sucrose analogs: an attractive (bio)source for glycodiversification. Daudé D, Remaud-Siméon M, and André I Nat. Prod. Rep. 29(9), 945-60, (2012)

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Dissecting the effects of nitrate, sucrose and osmotic potential on Arabidopsis root and shoot system growth in laboratory assays. Roycewicz P and Malamy JE Philos. Trans. R. Soc. Lond., B, Biol. Sci. 367(1595), 1489-500, (2012)

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CuAAC-mediated diversification of aminoglycoside-arginine conjugate mimics by non-reducing di- and trisaccharides. Westermann B, Dörner S, Brauch S, et al. Carbohydr. Res. 371, 61-7, (2013)

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Isolation of glycine betaine and proline betaine from human urine. Assessment of their role as osmoprotective agents for bacteria and the kidney. Chambers ST and Kunin CM J. Clin. Invest. 79(3), 731-7, (1987)

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Investigation into the controversial association of Streptococcus gallolyticus with colorectal cancer and adenoma. Abdulamir AS BMC Cancer 9, 403, (2009)

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Slower recovery in space before collapse of connected populations. Dai L, Korolev KS, and Gore J Nature 496(7445), 355-8, (2013)

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Glucagon-like peptide-1 receptor-mediated endosomal cAMP generation promotes glucose-stimulated insulin secretion in pancreatic β-cells. Kuna RS, Girada SB, Asalla S, et al. Am. J. Physiol. Endocrinol. Metab. 305(2), E161-70, (2013)

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Effects of sucrose oleate and sucrose laureate on in vivo human stratum corneum permeability. Ayala-Bravo HA, Quintanar-Guerrero D, Naik A, et al. Pharm. Res. 20(8), 1267-73, (2003)

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Melanocortin 4 receptors in autonomic neurons regulate thermogenesis and glycemia. Berglund ED, Liu T, Kong X, et al. Nat. Neurosci. 17(7), 911-3, (2014)

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Calcium-permeable AMPA receptors in the nucleus accumbens regulate depression-like behaviors in the chronic neuropathic pain state. Goffer Y, Xu D, Eberle SE, et al. J. Neurosci. 33(48), 19034-44, (2013)

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A randomized, controlled trial of sucrose analgesia in infants younger than 90 days of age who require bladder catheterization in the pediatric emergency department. Rogers AJ, Greenwald MH, Deguzman MA, et al. Acad. Emerg. Med. 13(6), 617-22, (2006)

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Distribution of suramin, an antitrypanosomal drug, across the blood-brain and blood-cerebrospinal fluid interfaces in wild-type and P-glycoprotein transporter-deficient mice. Lisa Sanderson et al Antimicrob. Agents Chemother. 51, 3136-46, (2007)

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Amphiphilic copolymers of sucrose methacrylate and acrylic monomers: bio-based materials from renewable resource. de Oliveira HF and Felisberti MI Carbohydr. Polym. 94(1), 317-22, (2013)

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Biophysical characteristics reveal neural stem cell differentiation potential. Labeed FH PLoS ONE 6(9), e25458, (2011)

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Influence of T-2 and HT-2 toxin on the blood-brain barrier in vitro: new experimental hints for neurotoxic effects. Weidner M, Hüwel S, Ebert F, et al. PLoS ONE 8(3), e60484, (2013)

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Nasal lavage natural killer cell function is suppressed in smokers after live attenuated influenza virus. Horvath KM, Herbst M, Zhou H, et al. Respir. Res. 12, 102, (2011)

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Hypothalamic inflammation without astrogliosis in response to high sucrose intake is modulated by neonatal nutrition in male rats. Fuente-Martín E, García-Cáceres C, Díaz F, et al. Endocrinology 154(7), 2318-30, (2013)

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Sucrose ingestion induces rapid AMPA receptor trafficking. Tukey DS, Ferreira JM, Antoine SO, et al. J. Neurosci. 33(14), 6123-32, (2013)

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Cross-talk interactions of exogenous nitric oxide and sucrose modulates phenylpropanoid metabolism in yellow lupine embryo axes infected with Fusarium oxysporum. Morkunas I, Formela M, Floryszak-Wieczorek J, et al. Plant Sci. 211, 102-21, (2013)

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Improving starch yield in cereals by over-expression of ADPglucose pyrophosphorylase: expectations and unanticipated outcomes. Tuncel A and Okita TW Plant Sci. 211, 52-60, (2013)

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Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Lei Du-Cuny et al Bioorg. Med. Chem. 17, 6983-92, (2009)

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Hygienic behavior in honey bees (Hymenoptera: Apidae): effects of brood, food, and time of the year. Bigio G, Schürch R, and Ratnieks FL J. Econ. Entomol. 106(6), 2280-5, (2013)

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High voltage with little current as an unconditional stimulus for taste avoidance conditioning in Lymnaea stagnalis. Takigami S, Sunada H, Lukowiak K, et al. Neurosci. Lett. 555, 149-53, (2013)

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Dual-porosity model of solute diffusion in biological tissue modified by electroporation. Mahnič-Kalamiza S, Miklavčič D, and Vorobiev E Biochim. Biophys. Acta 1838(7), 1950-66, (2014)

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Analysis of interactions between intraflagellar transport proteins. Behal RH and Cole DG Meth. Enzymol. 524, 171-94, (2013)

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SMU.746-SMU.747, a putative membrane permease complex, is involved in aciduricity, acidogenesis, and biofilm formation in Streptococcus mutans. Król JE, Biswas S, King C, et al. J. Bacteriol. 196(1), 129-39, (2014)

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Influence of sucrose esters on the in vivo percutaneous penetration of octyl methoxycinnamate formulated in nanocapsules, nanoemulsion, and emulsion. Calderilla-Fajardo SB, Cázares-Delgadillo J, Villalobos-García R, et al. Drug Dev. Ind. Pharm. 32(1), 107-13, (2006)

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Structure and expression profile of the sucrose synthase gene family in the rubber tree: indicative of roles in stress response and sucrose utilization in the laticifers. Xiao X, Tang C, Fang Y, et al. FEBS J. 281(1), 291-305, (2014)

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Structures of acylated sucroses from the flower buds of Prunus mume. Fujimoto K, Nakamura S, Matsumoto T, et al. J. Nat. Med. 68(3), 481-7, (2014)

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Neuronal plasticity and multisensory integration in filial imprinting. Town, SM PLoS ONE 6(3), e17777, (2011)

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Branching pattern of gluco-oligosaccharides and 1.5kDa dextran grafted by the α-1,2 branching sucrase GBD-CD2. Brison Y, Laguerre S, Lefoulon F, et al. Carbohydr. Polym. 94(1), 567-76, (2013)

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Green synthesis of silver nanoparticles using white sugar. Meshram SM, Bonde SR, Gupta IR, et al. IET Nanobiotechnol. 7(1), 28-32, (2013)

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Positive and negative selection using the tetA-sacB cassette: recombineering and P1 transduction in Escherichia coli. Li XT, Thomason LC, Sawitzke JA, et al. Nucleic Acids Res. 41(22), e204, (2013)

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A simple method for the elimination of platelets from the lymphocyte-platelet mixture by sucrose. Chanarat P and Chiewsilp P Am. J. Clin. Pathol. 63(2), 237-9, (1975)

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Sucrose hydrolytic enzymes: old enzymes for new uses as biocatalysts for medical applications. Pang H, Du L, Pei J, et al. Curr. Top. Med. Chem 13(10), 1234-41, (2013)

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Comparison of the effects of slowly and rapidly absorbed carbohydrates on postprandial glucose metabolism in type 2 diabetes mellitus patients: a randomized trial. Ang M and Linn T Am. J. Clin. Nutr. 100(4), 1059-68, (2014)

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An improved process of isomaltooligosaccharide production in kimchi involving the addition of a Leuconostoc starter and sugars. Cho SK, Eom HJ, Moon JS, et al. Int. J. Food Microbiol. 170, 61-4, (2014)

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Gastric permeability to sucrose is increased in portal hypertensive gastropathy. Giofré MR, Meduri G, Pallio S, et al. Eur. J. Gastroenterol. Hepatol. 12(5), 529-33, (2000)

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The genetics of a putative social trait in natural populations of yeast. Bozdag GO and Greig D Mol. Ecol. 23(20), 5061-71, (2014)

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Bacterial maximum non-inhibitory and minimum inhibitory concentrations of different water activity depressing solutes. Cebrián G, Arroyo C, Mañas P, et al. Int. J. Food Microbiol. 188, 67-74, (2014)

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Tylosema esculentum extractives and their bioactivity. Ofentse Mazimba et al Bioorg. Med. Chem. 19, 5225-30, (2011)

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Osmolyte effects on the self-association of concanavalin A: testing theoretical models. Silvers TR and Myers JK Biochemistry 52(51), 9367-74, (2013)

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Hospitalized infants who hurt: a sweet solution with oral sucrose. Pasek TA and Huber JM Crit. Care Nurse 32(1), 61-9, (2012)

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Innovative sugar-insecticide feeding bioassay for adult female Anopheles gambiae (Diptera: Culicidae). Stell FM, Roe RM, Arellano C, et al. J. Med. Entomol. 50(4), 804-15, (2013)

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Identification and characterization of the Populus sucrose synthase gene family. An X, Chen Z, Wang J, et al. Gene 539(1), 58-67, (2014)

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Research progresses on the key enzymes involved in sucrose metabolism in maize. Ren X and Zhang J Carbohydr. Res. 368, 29-34, (2013)

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Increased expression of c-Jun in nonalcoholic fatty liver disease. Dorn C, Engelmann JC, Saugspier M, et al. Lab. Invest. 94(4), 394-408, (2014)

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Heterologous expression of AtPAP2 in transgenic potato influences carbon metabolism and tuber development. Zhang Y, Sun F, Fettke J, et al. FEBS Lett. 588(20), 3726-31, (2014)

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Disaccharides in urine samples as markers of intravenous abuse of methadone and buprenorphine. Jungen H, Andresen-Streichert H, Müller A, et al. J. Anal. Toxicol. 37(9), 652-8, (2013)

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Endolysosomal transport of newly-synthesized cathepsin D in a sucrose model of lysosomal storage. Hamer I and Jadot M Exp. Cell Res. 309(2), 284-95, (2005)

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Effects of combined exogenous dextranase and sodium fluoride on Streptococcus mutans 25175 monospecies biofilms. Yang YM, Jiang D, Qiu YX, et al. Am. J. Dent. 26(5), 239-43, (2013)

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Physiological responses of biomass allocation, root architecture, and invertase activity to copper stress in young seedlings from two populations of Kummerowia stipulacea (maxim.) Makino. Zhang L, Pan Y, Lv W, et al. Ecotoxicol. Environ. Saf. 104, 278-84, (2014)

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First evidence of sucrose biosynthesis by single cyanobacterial bimodular proteins. Martínez-Noël GM, Cumino AC, Kolman Mde L, et al. FEBS Lett. 587(11), 1669-74, (2013)

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Pre-emptive penile ring block with sucrose analgesia reduces pain response to neonatal circumcision. Roman-Rodriguez CF, Toussaint T, Sherlock DJ, et al. Urology 83(4), 893-8, (2014)

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Effects of a nonnutritive sweetener on body adiposity and energy metabolism in mice with diet-induced obesity. Mitsutomi K, Masaki T, Shimasaki T, et al. Metabolism 63(1), 69-78, (2014)

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Effect of buffer systems and disaccharides concentration on Podoviridae coliphage stability during freeze drying and storage. Dini C and de Urraza PJ Cryobiology 66(3), 339-42, (2013)

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Electrodynamic pressure modulation of protein stability in cosolvents. Damodaran S Biochemistry 52(46), 8363-73, (2013)

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Effect of heavy metals and phenol on bacterial decolourisation and COD reduction of sucrose-aspartic acid Maillard product. Yadav S and Chandra R J. Environ. Sci. (China) 25(1), 172-80, (2013)

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Factors affecting microbial fuel cell acclimation and operation in temperate climates. Michie IS, Kim JR, Dinsdale RM, et al. Water Sci. Technol. 67(11), 2568-75, (2013)

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Establishment of cell suspension cultures of two Costa Rican Jatropha species (Euphorbiaceae). Solís-Ramos LY, Carballo LM, and Valdez-Melara M Rev. Biol. Trop. 61(3), 1095-107, (2013)

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Erosive and cariogenicity potential of pediatric drugs: study of physicochemical parameters. Xavier AF, Moura EF, Azevedo WF, et al. BMC Oral Health 13, 71, (2013)

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Bioproduction and optimization of rosmarinic acid production in Solenostemon scutellarioides through media manipulation and conservation of high yielding clone via encapsulation. Sahu R, Dewanjee S, and Gangopadhyay M Nat. Prod. Commun. 8(9), 1275-8, (2013)

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Early life stage (ELS) toxicity of sucralose to fathead minnows, Pimephales promelas. Stoddard KI and Huggett DB Bull. Environ. Contam. Toxicol. 93(4), 383-7, (2014)

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Transcriptome analysis of grain-filling caryopses reveals the potential formation mechanism of the rice sugary mutant. Li FP, Yoon MY, Li G, et al. Gene 546(2), 318-26, (2014)

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The effect of selected polymorphisms of the dopamine receptor gene DRD2 and the ANKK-1 on the preference of concentrations of sucrose solutions in men with alcohol dependence. Jabłoński M, Jasiewicz A, Kucharska-Mazur J, et al. Psychiatr. Danub. 25(4), 371-8, (2013)

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In vitro flowering--a system for tracking floral organ development in Dendrocalamus hamiltonii Nees et Arn. ex Munro. Kaur D, Thapa P, Sharma M, et al. Indian J. Exp. Biol. 52(8), 825-34, (2014)

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Trehalose is not a universal solution for solid lipid nanoparticles freeze-drying. Doktorovova S, Shegokar R, Fernandes L, et al. Pharm. Dev. Technol. 19(8), 922-9, (2014)

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Physicochemical and structural characterization of iron-sucrose formulations: a comparative study. Barot BS, Parejiya PB, Mehta DM, et al. Pharm. Dev. Technol. 19(5), 513-20, (2014)

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Is sucrose required in open pulled straw (OPS) vitrification of mouse embryos? Al Yacoub AN, Gauly M, and Holtz W Cryo. Letters 34(5), 466-70, (2013)

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GC-MS and MALDI-TOF MS profiling of sucrose esters from Nicotiana tabacum and N. rustica. Haliński ŁP and Stepnowski P Z. Naturforsch. C 68(5-6), 210-22, (2013)

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Effect of a rice bran fiber diet on serum glucose levels of diabetic patients in Brazil. Rodrigues Silva C, Dutra de Oliveira JE, de Souza RA, et al. Arch. Latinoam. Nutr. 55(1), 23-7, (2005)

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Sucrose and oxidants. Keshvani AA J. Pediatr. 164(1), 220, (2014)

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Merck 14,8881

Beil. 17,V,8,399

Corp MSDS 1 (2), 3192:D / FT-IR 1 (1), 196:B / FT-IR 2 (1), 283:B / FT-NMR 1 (1), 305:C / IR-Spectra (2), 109:H / IR-Spectra (3), 119:A / NMR-Reference 2 (2), 912:A / RegBook 1 (1), 195:K / Sigma FT-IR 1 (1), 1142:A / Sigma FT-IR 1 (1), 1142:B / Structure Index 1, 27:B:2

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