• USA Home
  • V8138 - Vancomycin hydrochloride from Streptomyces orientalis

EMAIL THIS PAGE TO A FRIEND
V8138 Sigma-Aldrich

Vancomycin hydrochloride from Streptomyces orientalis

meets USP testing specifications

  • CAS Number 1404-93-9

  • Empirical Formula (Hill Notation) C66H75Cl2N9O24 · HCl

  • Molecular Weight 1485.71

  •  Beilstein Registry Number 3704657

  •  PubChem Substance ID 24278773

  • Popular Documents:  Specification Sheet (PDF)  

Purchase

Properties

Related Categories Analytical/Chromatography, Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics T-Z,
potency   ≥900 μg per mg (as vancomycin base)
solubility   H2O: soluble50 g/L
suitability   meets USP testing specifications
Mode of action   cell wall synthesis | interferes
antibiotic activity spectrum   Gram-positive bacteria
storage temp.   2-8°C

Description

Biochem/physiol Actions

Glycopeptide antibiotic
Mode of action: Used to block bacterial cell wall biosynthesis at the level of peptidoglycan biosynthesis by inhibiting incorporation of terminal D-alanyl-D-alanine moieties of the NAM/NAG-peptides.
Antimicrobial spectrum: Gram-positive bacteria

Other Notes

Studies on bond strength in vancomycin-peptide complexes. Structure of vancomycin and its complex with acetyl-D-alanyl-D-alanine.

Packaging

1, 5 g in glass bottle

250 mg in glass bottle

Price and Availability

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
YW4380000

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Inhibition of Cell Wall Biosynthesis by Antibiotics

Antibiotics are molecules that specifically target and kill cells. The term antibiotic is frequently used interchangeably with the word antibacterial, but antiviral, antifungal and antineoplastic com...
BioFiles 2006, 1.4, 7.
Keywords: Antibiotics, Antifungals, Antivirals, Building blocks, Glycosylations, Metabolism

Peer-Reviewed Papers
15

References

Set your institution to view full text papers.
Related Products

related product

Product #

Description

Add to Cart

08168 Timestrip Plus 8 °C

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?