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X4251 Sigma-Aldrich

XTT sodium salt

analytical standard, ≥90%

Synonym: 2,3-Bis(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide inner salt

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Properties

Related Categories Additional Drugs, Analytical Standards, Analytical/Chromatography, Pharmaceuticals, Illicit Drugs & Alcohol
grade   analytical standard
InChI Key   JACYMBNQPPWQML-UHFFFAOYSA-M
assay   ≥90%
form   neat
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
format   neat
storage temp.   2-8°C

Description

Application

XTT has been used in conjunction with phenazine methosulfate (PMS) to screen human cancer cell lines. The tetrazolium dye has also been used to study fungal cell damage, in testing antimicrobial susceptibility of staphylococci, and in Candida biofilm research. Limitations to the XTT assay have been reported.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

100, 500 mg in glass bottle

Principle

In living cells, XTT is metabolically reduced to produce a colorimetric, water-soluble formazan product.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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