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00189 Sigma

Sulfadimidine solution

1 mg/mL in H2O

Synonym: Sulfamethazine solution

  • CAS Number 57-68-1

  • Empirical Formula (Hill Notation) C12H14N4O2S

  • Molecular Weight 278.33

  •  Beilstein Registry Number 261304

  •  MDL number MFCD00006066

  •  PubChem Substance ID 329747014

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Properties

Related Categories Antibiotics, Antibiotics A to Z, Antibiotics N-S, Biochemicals and Reagents
InChI Key   ASWVTGNCAZCNNR-UHFFFAOYSA-N
form   liquid
concentration   1 mg/mL in H2O
color   colorless
Mode of action   enzyme | inhibits
antibiotic activity spectrum   Gram-negative bacteria
  Gram-positive bacteria

Description

Packaging

10ML

Application

Sulfadimidine is used to induce cytochrome P450 3A4 (CYP3A4) and to inhibit dihydrofolate reductase (DHFR). It was used to study amantadine acetylation.

Biochem/physiol Actions

Sulfadimidine is a competitive inhibitor of dihydropteroate synthetase to block the synthesis of folic acid. It acts as an inhibitor of dihydrofolate reductase (DHFR).

Other Notes

Conditions for safe storage,including any incompatibilities Keep container tightly closed in a dry and well-ventilated place.Store under inert gas. Light sensitive.

Price and Availability

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
nwg

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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