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01423 Sigma

N-Acetyl-D-penicillamine

for HPLC derivatization, ≥99.0% (T)

Synonym: N-Acetyl-3-mercapto-D-valine, NAP, NAPA

  • CAS Number 15537-71-0

  • Empirical Formula (Hill Notation) C7H13NO3S

  • Molecular Weight 191.25

  •  Beilstein Registry Number 1724742

  •  EC Number 239-585-4

  •  MDL number MFCD00078887

  •  PubChem Substance ID 329747269

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Properties

Related Categories A - H, Amino Acids, Analytical Reagents, Analytical/Chromatography, Biochemicals and Reagents,
grade   for HPLC derivatization
InChI Key   MNNBCKASUFBXCO-YFKPBYRVSA-N
assay   ≥99.0% (T)
optical activity   [α]20/D +10±2°, c = 1% in ethanol
mp   185-190 °C (dec.)

Description

Application

Chiral reagent for the precolumn derivatization of amino acids or amino alcohols; the diastereoisomers formed can be efficiently resolved by HPLC on conventional reversed-phase columns

Biochem/physiol Actions

N-Acetyl-D-penicillamine (NAP or NAPA), a thiol compound, is often used as a control molecule in studies involving nitric oxide donor molecules such as S-nitroso-N-acetyl-dl-penicillamine (SNAP) and sodium nitroprusside (SNP). N-acetyl-D-penicillamine (NAPA) is also used as a heavy metal chelator.

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Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

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