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02070 Sigma

Adenosine 5′-triphosphate P3-[1-(2-nitrophenyl)ethyl ester] disodium salt

≥95% (HPLC)

Synonym: ‘Caged ATP’, NPE caged ATP

  • CAS Number 171800-68-3

  • Empirical Formula (Hill Notation) C18H21N6Na2O15P3

  • Molecular Weight 700.29

  •  MDL number MFCD00077294

  •  PubChem Substance ID 24845222

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Properties

Related Categories ATPase, Biochemicals and Reagents, Enzyme Substrates, Enzymes, Inhibitors, and Substrates, Substrates by Enzyme More...
InChI Key   DWGOHIKVVKFGGU-DZHDPEGHSA-L
assay   ≥95% (HPLC)
storage temp.   −20°C

Description

Other Notes

Used to study intracellular mechanisms.; Irradiation with a short light pulse of 360 nm wavelength releases the parent compound from its cage, resulting in a time- and quantity-specific concentration increase of ATP within the cell.; Relaxation of muscle fibres by photolysis of caged ATP; Caged ATP as a tool in active transport research

Application

Adenosine 5′-triphosphate γ-(1-[2-nitrophenyl]ethyl) ester (“Caged” ATP) is used as a photolyzing substrate of luciferase-mediated firefly bioluminescence and other ATP-dependent photolytic processes. Caged ATP has also been used to study the dynamics of ATP-driven linear molecular motors such as myosin Va. Caged ATP is used to study intracellular mechanisms; Irradiation with a short light pulse of 360 nm wavelength releases the parent compound from its cage resulting in a time- and quantity-specific concentration increase of ATP within the cell; Relaxation of muscle fibres by photolysis of caged ATP.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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