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02110 Sigma

S-(5′-Adenosyl)-L-methionine p-toluenesulfonate

≥85% (HPCE)

Synonym: AdoMet

  • CAS Number 71914-80-2

  • Empirical Formula (Hill Notation) C22H30N6O8S2

  • Molecular Weight 570.64

  •  MDL number MFCD00145264

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Properties

Related Categories Cell Biology, Coenzymes and Cofactors, Nutrition Research, Vitamins
InChI Key   VHPOFDUCFKOUHV-XKGORWRGSA-N
assay   ≥85% (HPCE)
impurities   ≤5% water
solubility   H2O: soluble0.1 g/mL, clear
storage temp.   −20°C

Description

Biochem/physiol Actions

Methyl donor; cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in liver where 85% of all methylation reactions occur. It is also involved in regulating liver function, growth, and response to injury.

Other Notes

Same product — same quality — now Sigma brand

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
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A2408 S-(5′-Adenosyl)-L-methionine p-toluenesulfonate salt, from yeast (L-methionine enriched), ≥80% (HPLC), ≥80% (spectrophotometric assay)

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