• USA Home
  • 03699 - Ethylenediaminetetraacetic acid tetrasodium salt hydrate

EMAIL THIS PAGE TO A FRIEND
03699 Sigma

Ethylenediaminetetraacetic acid tetrasodium salt hydrate

BioUltra, ≥99.0% (KT)

Synonym: EDTA tetrasodium salt, Edathamil, Tetrasodium ethylenediaminetetraacetate hydrate

  • CAS Number 194491-31-1

  • Linear Formula (NaOOCCH2)2NCH2CH2N(CH2COONa)2 · xH2O

  • Molecular Weight 380.17 (anhydrous basis)

  •  Beilstein Registry Number 3861753

  •  EC Number 200-573-9

  •  MDL number MFCD00150025

  •  PubChem Substance ID 329747780

Purchase

Properties

Related Categories Biochemicals and Reagents, Chelators More...
InChI Key   GXFFSKMBMYHTAE-UHFFFAOYSA-J
product line   BioUltra
assay   ≥99.0% (KT)
impurities   insoluble matter, passes filter test
pH   11.0-12.0 (25 °C, 0.1 M in H2O)
solubility   H2O: soluble0.1 M at 20 °C, clear, colorless
anion traces   chloride (Cl-): ≤100 mg/kg
  sulfate (SO42-): ≤100 mg/kg
cation traces   Al: ≤5 mg/kg
  As: ≤0.1 mg/kg
  Ba: ≤5 mg/kg
  Bi: ≤5 mg/kg
  Ca: ≤10 mg/kg
  Cd: ≤5 mg/kg
  Co: ≤5 mg/kg
  Cr: ≤5 mg/kg
  Cu: ≤5 mg/kg
  Fe: ≤5 mg/kg
  K: ≤50 mg/kg
  Li: ≤5 mg/kg
  Mg: ≤5 mg/kg
  Mn: ≤5 mg/kg
  Mo: ≤5 mg/kg
  Ni: ≤5 mg/kg
  Pb: ≤5 mg/kg
  Sr: ≤5 mg/kg
  Zn: ≤5 mg/kg
λ   0.1 M in H2O
UV absorption   λ: 260 nm Amax: ≤1.5
  λ: 280 nm Amax: ≤0.06

Description

Preparation Note

Soluble in water at room temperature up to 1.45 M. The pH of this solution will be approximately 10 to 11 and will be rather viscous.

Application

EDTA is an inhibitor of metalloproteases, at effective concentrations of 1-10 mM. EDTA acts as a chelator of the zinc ion in the active site of metalloproteases, and can also inhibit other metal ion-dependent proteases such as calcium-dependent cysteine proteases. For use as an anticoagulant, disodium or tripotassium salts of EDTA are most commonly used. The optimal concentration is 1.5 mg per ml of blood.

Price and Availability

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Target organs 
Respiratory Tract
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
2

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

Set your institution to view full text papers.
Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?