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04076 Sigma

6-(p-Toluidino)-2-naphthalenesulfonyl chloride

suitable for fluorescence, ≥98.0% (HPLC)

Synonym: 2,6-TNS-Cl, 6-(4-Methylanilino)naphthalene-2-sulfonylchloride, 6-[(4-methylphenyl)amino]-2-naphthalenesulfonylchloride

  • CAS Number 62778-24-9

  • Empirical Formula (Hill Notation) C17H14ClNO2S

  • Molecular Weight 331.82

  •  Beilstein Registry Number 6521872

  •  MDL number MFCD00037749

  •  PubChem Substance ID 329747873

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Properties

Related Categories Alphabetical, Biochemicals and Reagents, Environmental Sensitive Membrane Probes, Fluorescent Indicators and Probes, Fluorescent Probes, Labels, Particles and Stains,
InChI Key   NONZPGMJWHNDKP-UHFFFAOYSA-N
assay   ≥98.0% (HPLC)
solubility   DMF: soluble
  acetonitrile: soluble
fluorescence   λex 381 nm in methanol
suitability   suitable for fluorescence
storage temp.   2-8°C

Description

Analysis Note

Emmax: none
do not dissolve in DMSO

Other Notes

Probe for determining the polarity in biological matrices

Application

6-(p-Toluidino)-2-naphthalenesulfonyl chloride is a fluorescent, hydrophobic probe utilized for labeling peptides to monitor conformational changes of a molecular assembly by measuring alterations in fluorescence intensity .

Price and Availability

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles

Articles

Sensor Dyes

In 1998 R.F. Furchgott, L.J. Ignarro, and F. Murad received the Nobel Prize in Physiology and Medicine for their discoveries concerning nitric oxide as a signaling molecule in the cardiovascular syst...
Monika Baeumle
BioFiles 2011, 6.3, 23.
Keywords: Applications, Biochemistry, Biological processes, Cancer, Cardiovascular, Central Nervous System, Diseases, Extinction coefficient, Indicators, Inflammation, Methods, Microscopy, Neurotransmission, Sol-gel, Type

Peer-Reviewed Papers
15

References

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