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04259 Sigma

N-Ethylmaleimide

BioUltra, ≥99.0% (HPLC)

Synonym: NEM

  • CAS Number 128-53-0

  • Empirical Formula (Hill Notation) C6H7NO2

  • Molecular Weight 125.13

  •  Beilstein Registry Number 112448

  •  EC Number 204-892-4

  •  MDL number MFCD00005509

  •  PubChem Substance ID 329747899

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Properties

InChI Key   HDFGOPSGAURCEO-UHFFFAOYSA-N
product line   BioUltra
assay   ≥99.0% (HPLC)
impurities   insoluble matter, passes filter test
ign. residue   ≤0.05%
bp   210 °C(lit.)
mp   43-46 °C(lit.)
  44-47 °C
solubility   methanol: soluble1 M at 20 °C, clear, colorless
anion traces   chloride (Cl-): ≤50 mg/kg
  sulfate (SO42-): ≤100 mg/kg
cation traces   Al: ≤5 mg/kg
  Ba: ≤5 mg/kg
  Bi: ≤5 mg/kg
  Ca: ≤10 mg/kg
  Cd: ≤5 mg/kg
  Co: ≤5 mg/kg
  Cr: ≤5 mg/kg
  Cu: ≤5 mg/kg
  Fe: ≤5 mg/kg
  K: ≤50 mg/kg
  Li: ≤5 mg/kg
  Mg: ≤5 mg/kg
  Mn: ≤5 mg/kg
  Mo: ≤5 mg/kg
  Na: ≤50 mg/kg
  Ni: ≤5 mg/kg
  Pb: ≤5 mg/kg
  Sr: ≤5 mg/kg
  Zn: ≤5 mg/kg
absorption   absorption1M/382 nm, methanol cut-off
storage temp.   2-8°C
Gene Information   human ... SLC6A3(6531), SLC6A4(6532)

Description

Application

Reagent for the covalent modification of cysteine residues in proteins.

Biochem/physiol Actions

Augments currents from native M-channels in sympathetic neurons and acts as an opener for KCNQ2, KCNQ4 and KCNQ5 channels.

Sulfhydryl alkylating agent that inactivates NADP-dependent isocitrate dehydrogenase and many endonucleases.

Price and Availability

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN 2928 8(6.1) / PGII
WGK Germany 
3
RTECS 
UX9625000
Flash Point(F) 
163.4 °F
Flash Point(C) 
73 °C
Protocols & Articles
Peer-Reviewed Papers
15

References

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