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04260 Sigma

N-Ethylmaleimide

purum p.a., ≥99.0% (HPLC)

Synonym: NEM

  • CAS Number 128-53-0

  • Empirical Formula (Hill Notation) C6H7NO2

  • Molecular Weight 125.13

  •  Beilstein Registry Number 112448

  •  EC Number 204-892-4

  •  MDL number MFCD00005509

  •  PubChem Substance ID 329747901

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Properties

Related Categories Core Bioreagents, Enzyme Inhibitors, Research Essentials More...
InChI Key   HDFGOPSGAURCEO-UHFFFAOYSA-N
grade   purum p.a.
assay   ≥99.0% (HPLC)
ign. residue   ≤0.05%
bp   210 °C(lit.)
mp   43-46 °C(lit.)
  43-46 °C
anion traces   chloride (Cl-): ≤50 mg/kg
  sulfate (SO42-): ≤100 mg/kg
cation traces   Ca: ≤50 mg/kg
  Cd: ≤50 mg/kg
  Co: ≤50 mg/kg
  Cu: ≤50 mg/kg
  Fe: ≤50 mg/kg
  K: ≤100 mg/kg
  Na: ≤100 mg/kg
  Ni: ≤50 mg/kg
  Pb: ≤50 mg/kg
  Zn: ≤50 mg/kg
storage temp.   2-8°C
Gene Information   human ... SLC6A3(6531), SLC6A4(6532)

Description

Application

Reagent for the covalent modification of cysteine residues in proteins.

Biochem/physiol Actions

Augments currents from native M-channels in sympathetic neurons and acts as an opener for KCNQ2, KCNQ4 and KCNQ5 channels.

Sulfhydryl alkylating agent that inactivates NADP-dependent isocitrate dehydrogenase and many endonucleases.

Price and Availability


Laboratory Gloves
Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN 2928 8(6.1) / PGII
WGK Germany 
3
RTECS 
UX9625000
Flash Point(F) 
163.4 °F
Flash Point(C) 
73 °C
Protocols & Articles
Peer-Reviewed Papers
15

References

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