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05129 Sigma

L-Alanine

BioUltra, ≥99.5% (NT)

Synonym: (S)-2-Aminopropionic acid, L-α-Aminopropionic acid

  • CAS Number 56-41-7

  • Empirical Formula (Hill Notation) C3H7NO2

  • Molecular Weight 89.09

  •  Beilstein Registry Number 1720248

  •  EC Number 200-273-8

  •  MDL number MFCD00064410

  •  PubChem Substance ID 329747639

  •  eCl@ss 32160406

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Properties

Related Categories Amino Acids, BioUltra, Biochemicals and Reagents More...
InChI Key   QNAYBMKLOCPYGJ-REOHCLBHSA-N
product line   BioUltra
assay   ≥99.5% (NT)
form   powder or crystals
optical activity   [α]20/D +14.0±1.0°, c = 5% in 5 M HCl
impurities   insoluble matter, passes filter test
  ≤0.3% foreign amino acids
ign. residue   ≤0.05%
loss   ≤0.05% loss on drying, 20 °C (HV)
pH   5.5-7.0 (25 °C, 1 M in H2O)
solubility   H2O: soluble1 M at 20 °C, clear, colorless
anion traces   chloride (Cl-): ≤50 mg/kg
  sulfate (SO42-): ≤50 mg/kg
cation traces   Al: ≤5 mg/kg
  As: ≤0.1 mg/kg
  Ba: ≤5 mg/kg
  Bi: ≤5 mg/kg
  Ca: ≤10 mg/kg
  Cd: ≤5 mg/kg
  Co: ≤5 mg/kg
  Cr: ≤5 mg/kg
  Cu: ≤5 mg/kg
  Fe: ≤5 mg/kg
  K: ≤50 mg/kg
  Li: ≤5 mg/kg
  Mg: ≤5 mg/kg
  Mn: ≤5 mg/kg
  Mo: ≤5 mg/kg
  NH4+: ≤100 mg/kg
  Na: ≤50 mg/kg
  Ni: ≤5 mg/kg
  Pb: ≤5 mg/kg
  Sr: ≤5 mg/kg
  Zn: ≤5 mg/kg
λ   1 M in H2O
UV absorption   λ: 260 nm Amax: ≤0.03
  λ: 280 nm Amax: ≤0.02
Gene Information   human ... CA1(759), CA2(760)

Description

Other Notes

Postulated salting-in effect on proteins; Growth requirement of a variety of microorganisms.

Biochem/physiol Actions

Alanine is a nonessential amino acid that plays a key role in the glucose-alanine cycle between muscle tissue and the liver. In amino acid-degrading tissues such as muscle, amino groups are pooled as glutamate by transamination reactions. The amino group of glutamate is transferred to pyruvate via alanine aminotransferase, forming alanine and α-ketoglutarate. The alanine is passed into the blood and transported to the liver. This reaction is reversed in the liver where pyruvate can be used in gluconeogenesis to form glucose, which may return to other tissues through the circulatory system. Increased alanine levels correlate with higher blood pressure, energy intake, cholesterol levels, and body mass index.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
1

Documents

Certificate of Analysis

Protocols & Articles

Related Content

Amino Acids Reference Chart

The hydrophobicity index is a measure of the relative hydrophobicity, or how soluble an amino acid is in water. In a protein, hydrophobic amino acids are likely to be found in the interior, whereas h...

Peer-Reviewed Papers
15

References

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