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08520 Sigma

Quin-2

suitable for fluorescence, ≥95% (HPLC)

Synonym: 2-[(2-Amino-5-methylphenoxy)methyl]-6-methoxy-8-aminoquinoline-N,N,N′,N′-tetraacetic acid tetrapotassium salt, 2-{[2-Bis-(carboxymethyl)amino-5-methylphenoxy]-methyl}-6-methoxy-8-bis-(carboxymethyl)aminoquinoline tetrapotassium salt, Glycine,N-[2-[[8-[bis(carboxymethyl)amino]-6-methoxy-2-quinolinyl]methoxy]-4-methylphenyl]-N-(carboxymethyl)-,potassium salt (1:4), Quin 2, Tetrapotassium Salt, tetrapotassium 2-[[2-[[2-[bis(2-oxido-2-oxoethyl)amino]-5-methylphenoxy]methyl]-6-methoxyquinolin-8-yl]-(2-oxido-2-oxoethyl)amino]acetate

  • CAS Number 73630-23-6

  • Empirical Formula (Hill Notation) C26H23K4N3O10

  • Molecular Weight 693.87

  •  Beilstein Registry Number 5374262

  •  MDL number MFCD00065487

  •  PubChem Substance ID 24846193

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Properties

Related Categories Biochemicals and Reagents, Calcium Indicators, Chelators and Ion Probes, Chelators and Ion Probes for Flow Cytometry, Chelators and Ion Probes for Microscopy,
InChI Key   XAGUNWDMROKIFJ-UHFFFAOYSA-J
assay   ≥95% (HPLC)
solubility   H2O: soluble10 mg/mL
fluorescence   λex 332 nm; λem 493 nm in 0.1 M Tris pH 8.0, 10 mM Ca2+
suitability   suitable for fluorescence
storage temp.   2-8°C

Description

Other Notes

A fluorescent highly selective Ca++ indicator exhibiting fast uptake and release of Ca++; Calibration substance in the measurement of cytoplasmic free calcium

Application

Quin-2 has been demonstrated to be an indicator of Zn2+-protein complexes .

Price and Availability

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles

Articles

Sensor Dyes

In 1998 R.F. Furchgott, L.J. Ignarro, and F. Murad received the Nobel Prize in Physiology and Medicine for their discoveries concerning nitric oxide as a signaling molecule in the cardiovascular syst...
Monika Baeumle
BioFiles 2011, 6.3, 23.
Keywords: Applications, Biochemistry, Biological processes, Cancer, Cardiovascular, Central Nervous System, Diseases, Extinction coefficient, Indicators, Inflammation, Methods, Microscopy, Neurotransmission, Sol-gel, Type

Peer-Reviewed Papers
15

References

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